88918-84-7

Basic information

• Product Name: 4-Amino-N-methylbenzenemethanesulfonamide hydrochloride
• Synonyms: N-METHYL-(4-AMMONIOPHENYL)METHANESULFONAMIDE CHLORIDE;4-AMINO-N-METHYL-ALPHA-TOLUENESULPHONAMIDE HYDROCHLORIDE;4-AMINO-N-METHYL-ALPHA-TOLUENESULFONAMIDE HYDROCHLORIDE;BENZENEMETHANESULFONAMIDE, 4-AMINO-N-METHYL,HYDROCHLORIDE;4-Amino-N-methylbenzylsulphonamide hydrochloride~(4-Aminophenyl)-N-methylmethylensulphonamide hydrochloride;(4-Aminophenyl)-N-methylmethylenesulfonamideHCl;4-Amino-N-methylbenzylsulfonamideHCl;(4-aminophenyl)-n-methylmethylensulfonamide hydrochloride
• CAS NO: 88918-84-7
• Molecular Formula: C₈H₁₂N₂O₂S*ClH
• Molecular Weight: 236.72
• EINECS: 406-010-5
• Mol File: 88918-84-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 134 °C
• Boiling Point: 387.6°C at 760 mmHg
• Flash Point: 188.2°C
• Appearance: /
• Vapor Pressure: 3.25E-06mmHg at 25°C
• CAS DataBase Reference: 4-Amino-N-methylbenzenemethanesulfonamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-N-methylbenzenemethanesulfonamide hydrochloride(88918-84-7)
• EPA Substance Registry System: 4-Amino-N-methylbenzenemethanesulfonamide hydrochloride(88918-84-7)

Safety Data

• Hazard Codes: Xi,N
• Statements: 41-43-51/53
• Safety Statements: 24-26-37/39-61
• HazardClass: 9
• PackingGroup: III
• Hazardous Substances Data: 88918-84-7(Hazardous Substances Data)

Usage

Description

4-Amino-N-methylbenzenemethanesulfonamide hydrochloride is a chemical compound characterized by an aminobenzenesulfonamide structure with a methyl group and a hydrochloride salt. It is recognized for its antimicrobial properties and is being explored for its potential in cancer treatment.

Uses

Used in Pharmaceutical Industry:
4-Amino-N-methylbenzenemethanesulfonamide hydrochloride is used as an antibacterial agent for its ability to inhibit bacterial growth and protein synthesis, which is vital for bacterial survival.
Used in Oncology Research:
In the field of oncology, 4-Amino-N-methylbenzenemethanesulfonamide hydrochloride is used as a potential anticancer agent due to its demonstrated capacity to inhibit the growth of tumor cells, making it a subject of interest for further research and development in cancer therapies.

InChI:InChI=1/C8H12N2O2S.ClH/c1-10-13(11,12)6-7-2-4-8(9)5-3-7;/h2-5,10H,6,9H2,1H3;1H

Upstream product

• 85952-29-0 (4-nitro-phenyl)-methanesulfonic acid methylamide 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS

Indole derivatives of the general formula (I) are disclosed: where R1 is H or an alkyl or alkenyl group, R2 is H, or an alkyl, alkenyl, aryl, aralkyl or cycloalkyl group; R3 is H or an alkyl group; R4 and R5 are independently H or an alkyl or propenyl group or together form an aralkylidene group; and Alk is an optionally substituted alkylene chain; and their physiologically acceptable salts and solutes. These compounds are potentially useful for the treatment of migraine and may be formulated as pharmaceutical compositions in conventional manner. Various methods for the production of the compounds are disclosed including a Fischer-indole cyclization process