85952-29-0

Basic information

• Product Name: N-Methyl-1-(4-nitrophenyl)methanesulfonamide
• Synonyms: BENZENEMETHANESULFONAMIDE,N-METHYL-4-NITRO-;N-methyl-4-nitrotoluenesulphonamide;4-NITRO-N-METHTYL BENZENE METHANE SULFONAMIDE;4-Nitro-Methyl-Benzene-Methane-Sulfonamide;N-Methyl-4-nitro-ɑ-toluenesulfonamide, 98%;N-Methyl-4-nitro-^a-toluenesulfonamide, 98%;N-Methyl-4-nitro-alpha-toluenesulfonamide, 98%;N-Methyl-4-nitro-α-toluenesulfonamide
• CAS NO: 85952-29-0
• Molecular Formula: C₈H₁₀N₂O₄S
• Molecular Weight: 230.24
• Mol File: 85952-29-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 151-153°C
• Boiling Point: 417.5 °C at 760 mmHg
• Flash Point: 206.3 °C
• Appearance: /
• Density: 1.404 g/cm³
• Vapor Pressure: 3.53E-07mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: 2-8°C
• PKA: 10.69±0.40(Predicted)
• CAS DataBase Reference: N-Methyl-1-(4-nitrophenyl)methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methyl-1-(4-nitrophenyl)methanesulfonamide(85952-29-0)
• EPA Substance Registry System: N-Methyl-1-(4-nitrophenyl)methanesulfonamide(85952-29-0)

Safety Data

• Hazardous Substances Data: 85952-29-0(Hazardous Substances Data)

Usage

Uses

N-Methyl-1-(4-nitrophenyl)methanesulfonamide is a reagent used in hydrogenation reactors in the pharmaceutical industry.

InChI:InChI=1/C8H10N2O4S/c1-9-15(13,14)6-7-2-4-8(5-3-7)10(11)12/h2-5,9H,6H2,1H3

Upstream product

• 74-89-5 methylamine 
• 4025-75-6 (4-nitrophenyl)methanesulfonyl chloride 
• 1939-99-7 benzenesulfonyl chloride 
• 36639-50-6 Sodium 4-nitrobenzylsulphonate 
• 19299-41-3 N-methyl-1-phenylmethanesulfonamide 

Downstream Products

• 88918-84-7 4-Amino-N-methylbenzenemethanesulphonamide, hydrochloride 
• 765252-40-2 C₁₁H₁₆N₂O₄S 
• 264909-30-0 piperidine-2,3-dione-3-[4-[(N-methylaminosulfonyl)methyl]phenylhydrazone] 
• 109903-35-7 1-(4-aminophenyl)-N-methylmethanesulfonamide 
• 197580-86-2 N-ethoxycarbonyl-N-methyl-4-nitrobenzenemethanesulphonamide 
• 110654-61-0 N-Methyl-N-{[methyl-(4-nitro-phenylmethanesulfonyl)-amino]-methyl}-C-(4-nitro-phenyl)-methanesulfonamide 
• 94514-75-7 3-Methyl-6-nitro-3,4-dihydro-1H-benzo[d][1,2]thiazine 2,2-dioxide 

Relevant articles and documents

INHIBITORS OF PROTEIN KINASES

The present invention provides new compounds. The compounds are useful as CDK5 inhibitors, and accordingly they can be included in pharmaceuticals compositions for treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases. formula (I).

INHIBITORS OF PROTEIN KINASES

The present invention provides new compounds. The compounds are useful as CDK5 inhibitors, and accordingly they can be included in pharmaceuticals compositions for treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases. formula (I).

Intramolecular sulphonyl-amidomethylation. Part I. Cyclization of benzylsulphonamides

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