88919-22-6 Usage
Chemical Properties
Off-White Solid
Uses
Different sources of media describe the Uses of 88919-22-6 differently. You can refer to the following data:
1. An antimigraine agent. A Sumatriptan intermediate
2. 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (Didesmethyl Sumatriptan) (Sumatriptan EP Impurity E) is an antimigraine agent. A Sumatriptan intermediate.
Check Digit Verification of cas no
The CAS Registry Mumber 88919-22-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,9,1 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 88919-22:
(7*8)+(6*8)+(5*9)+(4*1)+(3*9)+(2*2)+(1*2)=186
186 % 10 = 6
So 88919-22-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H17N3O2S/c1-8-3-4-11-10(7-8)9(5-6-13)12(15(11)2)18(14,16)17/h3-4,7H,5-6,13H2,1-2H3,(H2,14,16,17)
88919-22-6Relevant articles and documents
N-Desmethyltriptans: One pot efficient synthesis of N-methyl-2-5- [substituted- 1H- indole-3-yl]ethanamines
Mittapelli, Vasantha,Ray, Puma Chandra,Chauhan, Yogendra Kumar,Datta, Debashish
experimental part, p. 590 - 594 (2010/01/06)
A straightforward and highly improved method to synthesize N-methyl-2-[5-[substituted-lH-indole-3-yl]ethanamines 4-6, which are the metabolites of tryptans 1-3, is reported. The significance of the process is its simplicity and efficiency in isolating the N- desmethyltriptans derivatives as a free base.