88918-76-7

Basic information

• Product Name: 3-(CyanoMethyl)-N-Methyl-1H-indole-5-MethanesulfonaMide
• Synonyms: 3-(CyanoMethyl)-N-Methyl-1H-indole-5-MethanesulfonaMide
• CAS NO: 88918-76-7
• Molecular Formula: C₁₂H₁₃N₃O₂S
• Molecular Weight: 263.31552
• Product Categories: Indole Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 88918-76-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 3-(CyanoMethyl)-N-Methyl-1H-indole-5-MethanesulfonaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(CyanoMethyl)-N-Methyl-1H-indole-5-MethanesulfonaMide(88918-76-7)
• EPA Substance Registry System: 3-(CyanoMethyl)-N-Methyl-1H-indole-5-MethanesulfonaMide(88918-76-7)

Safety Data

• Hazardous Substances Data: 88918-76-7(Hazardous Substances Data)

Usage

Uses

Sumatriptan (S810000) derivative.

Upstream product

• 67-66-3 chloroform 
• 88919-22-6 3-(2-aminoethyl)-1H-indole-5-yl-N-methyl methane sulphonamide 

Downstream Products

• 103628-44-0 5-[[(Methylamino)sulphonyl]methyl]-1H-indole-3-acetic acid 
• 88919-22-6 3-(2-aminoethyl)-1H-indole-5-yl-N-methyl methane sulphonamide 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS

Indole derivatives of the general formula (I) are disclosed: where R1 is H or an alkyl or alkenyl group, R2 is H, or an alkyl, alkenyl, aryl, aralkyl or cycloalkyl group; R3 is H or an alkyl group; R4 and R5 are independently H or an alkyl or propenyl group or together form an aralkylidene group; and Alk is an optionally substituted alkylene chain; and their physiologically acceptable salts and solutes. These compounds are potentially useful for the treatment of migraine and may be formulated as pharmaceutical compositions in conventional manner. Various methods for the production of the compounds are disclosed including a Fischer-indole cyclization process