88931-07-1

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 34418-91-2 2,3,4,5-tetrahydropyridine N-oxide 
• 56633-34-2 E/Z-1-(3,4-dimethoxyphenyl)-1,3-butadiene 

Downstream Products

• 89771-50-6 (+/-)-2-episubcosine II 
• 88931-06-0 (+/-)-subcosine I 
• 88931-04-8 (2RS,4RS,9aSR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-ol 
• 88931-05-9 4-(3,4-dimethoxyphenyl)octahydro-1H-quinolizin-2-ol 
• 88909-05-1 2-[2-Chloro-2-(3,4-dimethoxy-phenyl)-ethyl]-hexahydro-isoxazolo[2,3-a]pyridine 

Relevant academic research and scientific papers

Synthesis of (+/-)-Lasubine I and (+/-)-Subcosine I

(+/-)-Lasubine I and (+/-)-subcosine I were synthesised by a route involving as a key step a 1,3-dipolar cycloaddition.

Synthesis of (+/-)-Lasubine I and II and (+/-)-Subcosine I

The first total synthesis of lasubine I and II and subcosine I has been achieved.A crucial step of this synthesis involves thermal dipolar cycloaddition of 1-(3,4-dimethoxyphenyl)butadiene with 2,3,4,5-tetrahydropyridine 1-oxide, affording the E and