88931-04-8

Upstream product

• 88909-04-0 2(Z)-(3,4-dimethoxystyryl)-3,3a,4,5,6,7-hexahydro-2H-isoxazolo<2,3-a>pyridine 
• 88909-04-0 2(E)-(3,4-dimethoxystyryl)-3,3a,4,5,6,7-hexahydro-2H-isoxazolo<2,3-a>pyridine 
• 56633-34-2 E/Z-1-(3,4-dimethoxyphenyl)-1,3-butadiene 
• 97387-80-9 1-(3,4-dimethoxy-phenyl)-but-3-en-1-ol 
• 115881-08-8 N-<1-(3,4-dimethoxyphenyl)but-3-en-1-yl>glutarimide 
• 115881-09-9 1-[1-(3,4-Dimethoxy-phenyl)-but-3-enyl]-6-hydroxy-piperidin-2-one 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 34418-91-2 2,3,4,5-tetrahydropyridine N-oxide 
• 206749-06-6 1-[1-(3,4-Dimethoxy-phenyl)-3-trimethylsilanylmethyl-but-3-enyl]-6-hydroxy-piperidin-2-one 
• 206749-04-4 1-[1-(3,4-Dimethoxy-phenyl)-3-trimethylsilanylmethyl-but-3-enyl]-piperidine-2,6-dione 
• 88909-05-1 2-[2-Chloro-2-(3,4-dimethoxy-phenyl)-ethyl]-hexahydro-isoxazolo[2,3-a]pyridine 
• 89690-19-7 (4S*,9aR*)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-one 
• 144409-59-6 (R)-7,8,9,9a-tetrahydro-1H-quinolizin-2(6H)-one 
• 144375-66-6 4-Methoxy-1-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-3-triisopropylsilanyl-pyridinium; chloride 

Downstream Products

• 68622-78-6 (+)-subcosine I 
• 71480-97-2 2-(p-methoxyphenylpropionoyloxy)(a)-4-(3',4'-dimethoxyphenyl)(e)-trans-quinolizidine 
• 77092-60-5 2-(p-benzyloxyphenylpropionoyloxy)(a)-4-(3',4'-dimethoxyphenyl)(e)-trans-quinolizidine 
• 88931-06-0 (+/-)-subcosine I 
• 60352-71-8 Acetic acid (2R,4R,9aS)-4-(3,4-dimethoxy-phenyl)-octahydro-quinolizin-2-yl ester 
• 71480-99-4 2,2,3-Trichloro-3-(4-methoxy-phenyl)-propionic acid (2S,4S,9aS)-4-(3,4-dimethoxy-phenyl)-octahydro-quinolizin-2-yl ester 
• 71480-98-3 (Z)-2-Chloro-3-(4-methoxy-phenyl)-acrylic acid (2S,4S,9aS)-4-(3,4-dimethoxy-phenyl)-octahydro-quinolizin-2-yl ester 
• 77092-63-8 2-(p-hydroxyphenylpropionoyloxy)(a)-4-(3',4'-dimethoxyphenyl)(e)-trans-quinolizidine 

Relevant academic research and scientific papers

Rhodium-catalyzed intramolecular conjugate addition of vinylstannanes to?dihydro-4-pyridones: a simple method for stereoselective construction of 1-azabicyclic alkaloids

A straightforward route for the stereoselective synthesis of unsaturated quinolizidines and related higher homologs has been developed. Our results revealed that the rhodium complex [RhCl(cod)]2 is an effective catalyst for the intramolecular c

A synthesis of the quinolizidine alkaloids (±)-lasubine I and (±)-lasubine II

A total synthesis of (±)-lasubine I and (±)-lasubine II has been achieved in six steps from a β-hydroxyallylsilane synthon using intramolecular cyclization of allylsilane on N-acyliminium ion as a key step.

SYNTHESIS OF (+/-)-LASUBINE I

Using N-acyliminium cyclization as a key-step, the total synthesis of (+/-)-lasubine I has been achieved in six steps starting from veratraldehyde.

Synthesis of (+/-)-Lasubine I and II and (+/-)-Subcosine I

The first total synthesis of lasubine I and II and subcosine I has been achieved.A crucial step of this synthesis involves thermal dipolar cycloaddition of 1-(3,4-dimethoxyphenyl)butadiene with 2,3,4,5-tetrahydropyridine 1-oxide, affording the E and

Synthesis of (+/-)-Lasubine I and (+/-)-Subcosine I

(+/-)-Lasubine I and (+/-)-subcosine I were synthesised by a route involving as a key step a 1,3-dipolar cycloaddition.

General Synthetic Approach to the Quinolizidine Alkaloids via a -Cycloaddition

Two naturally occurring arylquinolizidinols have been synthesized via a -cycloaddition.