88945-42-0

Basic information

• Product Name: methyl 7H-imidazo[1,5-a]imidazol-2-ylimidoformate
• CAS NO: 88945-42-0
• Molecular Formula: C₇H₈N₄O
• Molecular Weight: 164.1646
• Mol File: 88945-42-0.mol

Chemical Properties

• Boiling Point: 338°C at 760 mmHg
• Flash Point: 158.2°C
• Density: 1.38g/cm³
• Vapor Pressure: 0.000101mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: methyl 7H-imidazo[1,5-a]imidazol-2-ylimidoformate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 7H-imidazo[1,5-a]imidazol-2-ylimidoformate(88945-42-0)
• EPA Substance Registry System: methyl 7H-imidazo[1,5-a]imidazol-2-ylimidoformate(88945-42-0)

Safety Data

• Hazardous Substances Data: 88945-42-0(Hazardous Substances Data)

Upstream product

• 540-61-4 2-aminoacetonitrile 
• 149-73-5 trimethyl orthoformate 

Relevant articles and documents

IMIDATES IN ORGANIC SYNTHESIS: METHYL N-CYANOMETHYLMETHANIMIDATE

Synthesis, preliminary properties and reactions of the reagent Methyl N-cyanomethylmethanimidate are reported.

Reagents for Bioorganic Synthesis: Preparation, Properties, and Reactions of Ethyl and Methyl N-(Cyanomethyl)methanimidates

An efficient procedure for the preparation of the reagents ethyl and methyl N-(cyanomethyl)methanimidates (NCCH2N=CHOR) (1a, R=Et; 1b, R=Me) is presented,along with their preliminary properties and reactions.The reaction of aminoacetonitrile hydrochloride with trialkyl orthoformate gave 4(5)-imidazolone.The reaction of aminoacetonitrile (free base) with the ortho ester, catalyzed by formic acid, gave methyl N-7H-imidazoimidazol-2-ylmethanimidate (6).The reaction of 1b with 2-aminothiazole and 2-aminopyrimidine, catalyzed by trimethylsilyl triflate, gave 2-(5'-imino-2'-imidazolin-1'-yl)thiazole (9) and 2-(5'-imino-2'-imidazolin-1'-yl)pyrimidine (10), respectively.Compound 10 underwent facile acid hydrolysis to form 2-(formylamino)pyrimidine (11).The reactions of 2-aminothiazole with 2 equiv of 1b or that of 10 with 1 equiv of 1b both provided 2-thiazole (12).