540-61-4

Basic information

• Product Name: AMINOACETONITRILE
• Synonyms: AMINOACETONITRILE;Glycinonitrile;2-Aminoacetonitrile;Acetonitrile, amino-;alpha-Aminoacetonitrile;amino-acetonitril;aminoacetonitrilefreebase;Cyanomethylamine
• CAS NO: 540-61-4
• Molecular Formula: C₂H₄N₂
• Molecular Weight: 56.07
• EINECS: 208-751-8
• Mol File: 540-61-4.mol
• Article Data: 22

Chemical Properties

• Melting Point: 101 °C
• Boiling Point: bp15 58° (partial decompn)
• Flash Point: 53.1°C
• Appearance: /
• Density: 0.7789 (rough estimate)
• Vapor Pressure: 1.99mmHg at 25°C
• Refractive Index: 1.4180 (estimate)
• Storage Temp.: −20°C
• PKA: 5.34(at 25℃)
• CAS DataBase Reference: AMINOACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: AMINOACETONITRILE(540-61-4)
• EPA Substance Registry System: AMINOACETONITRILE(540-61-4)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-40
• Safety Statements: 23-36
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• RTECS: AL7750000
• Hazardous Substances Data: 540-61-4(Hazardous Substances Data)

Usage

Uses

Aminoacetonitrile is used in preparation of the Heterocyclic compounds and their medical applications.

InChI:InChI=1/C2H4N2/c3-1-2-4/h1,3H2

Upstream product

• 50-00-0 formaldehyd 
• 74-90-8 hydrogen cyanide 
• 107-16-4 glycolonitrile 
• 22483-19-8 [2-Methyl-prop-(E)-ylideneamino]-acetonitrile 
• 67726-04-9 (1-Phenyl-cyclopentylamino)-acetonitrile; hydrochloride 
• 34557-54-5 methane 
• 79-01-6 Trichloroethylene 
• 188819-30-9 C₂H₄NO₃^(1-) 
• 6011-14-9 2-aminoacetonitrile hydrochloride 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 107-15-3 ethylenediamine 
• 85363-04-8 tert-butyl cyanomethylcarbamate 
• 7664-41-7 ammonia 
• 100-97-0 hexamethylenetetramine 

Downstream Products

• 6278-43-9 5-isopropylidene-imidazolidine-2,4-dithione 
• 5766-70-1 N,N'-Di-(cyanomethyl)-melamin 
• 87783-69-5 (2E)-N-(cyanomethyl)-3-phenylacrylamide 
• 16728-84-0 p-tolylaminoacetonitrile 
• 5692-27-3 2-benzamido-ethanenitrile 
• 22192-84-3 N-(cyanomethyl)-4-methoxybenzamide 
• 628-87-5 iminodiacetonitrile 
• 3009-97-0 N-phenylglycinonitrile 
• 412311-64-9 (5-amino-thiazol-2-yl)-carbamic acid ethyl ester 
• 18591-57-6 2,3-Diphenyl-6-hydroxypyrazine 
• 7327-60-8 nitrilotriacetonitrile 
• 408509-85-3 2-benzyl-thiazol-5-ylamine 
• 861055-62-1 N-phenylthioacetyl-glycine nitrile 
• 459-73-4 GlyOEt*HCl 

Relevant articles and documents

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Method for synthesizing aminoacetonitrile hydrochloride from hydrocyanic acid

The invention relates to the technical field of organic chemical synthesis. The method comprises the following steps: reacting hydrocyanic acid with formaldehyde to obtain a hydroxyacetonitrile aqueous solution, reacting hydroxyacetonitrile with ammonia to obtain an aminoacetonitrile aqueous solution, reacting aminoacetonitrile with hydrogen chloride, and concentrating, crystallizing, filtering and drying the obtained feed liquid to obtain aminoacetonitrile hydrochloride. The method provided by the invention is simple in technological process and mild in reaction condition, high-temperature and high-pressure operation is not involved, and used equipment is conventional equipment; except hydrocyanic acid, other raw materials are easy to obtain, and the raw material cost is low; waste waterand waste gas are small in amount and can be used indiscriminately, and only a small amount of ammonium chloride is generated; the product quality is good, and the appearance and content are higher than those of a sodium cyanide process.

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a manufacturing method of nitrile. Compared with the prior art, the manufacturing method has the characteristics of significantly reduced using amount of an ammonia source, low environmental pressure, low energy consumption, low production cost, high purity and yield of a nitrile product and the like, and nitrile with a more complex structure can be obtained. The invention also relates to a method for manufacturing corresponding amine from nitrile.