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540-61-4 Usage


Aminoacetonitrile, also known as 2-aminoacetonitrile or α-aminoacetonitrile, is an organic compound with the chemical formula CH3CH(NH2)CN. It is a colorless, toxic liquid that is soluble in water and has a variety of applications in the chemical and pharmaceutical industries due to its unique chemical properties.


Used in Pharmaceutical Industry:
Aminoacetonitrile is used as an intermediate in the synthesis of various heterocyclic compounds, which have significant medical applications. These heterocyclic compounds are often the core structures of many pharmaceutical drugs, making Aminoacetonitrile a crucial component in the development of new medications.
Used in Chemical Industry:
In the chemical industry, Aminoacetonitrile is utilized as a building block for the production of various organic compounds, such as amino acids, peptides, and other nitrogen-containing molecules. Its versatility in chemical reactions allows it to be a valuable asset in the synthesis of a wide range of products.

Check Digit Verification of cas no

The CAS Registry Mumber 540-61-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 540-61:
54 % 10 = 4
So 540-61-4 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017


1.1 GHS Product identifier

Product name 2-aminoacetonitrile

1.2 Other means of identification

Product number -
Other names Aminoacetonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:540-61-4 SDS

540-61-4Relevant articles and documents



, p. 2197 (1934)


Method for synthesizing aminoacetonitrile hydrochloride from hydrocyanic acid


Paragraph 0030; 0034; 0038; 0042; 0046; 0050; 0054; 0058, (2020/08/18)

The invention relates to the technical field of organic chemical synthesis. The method comprises the following steps: reacting hydrocyanic acid with formaldehyde to obtain a hydroxyacetonitrile aqueous solution, reacting hydroxyacetonitrile with ammonia to obtain an aminoacetonitrile aqueous solution, reacting aminoacetonitrile with hydrogen chloride, and concentrating, crystallizing, filtering and drying the obtained feed liquid to obtain aminoacetonitrile hydrochloride. The method provided by the invention is simple in technological process and mild in reaction condition, high-temperature and high-pressure operation is not involved, and used equipment is conventional equipment; except hydrocyanic acid, other raw materials are easy to obtain, and the raw material cost is low; waste waterand waste gas are small in amount and can be used indiscriminately, and only a small amount of ammonium chloride is generated; the product quality is good, and the appearance and content are higher than those of a sodium cyanide process.

New synthesis method of orotic acid


Paragraph 0019; 0035-0036; 0040-0041; 0045-0046, (2019/01/13)

The invention belongs to the field of organic chemistry and discloses a new synthesis method of orotic acid, comprising the following steps: S1: enabling glycolonitrile and ammonia wate to react, thusobtaining a reaction system a in which a product is aminoacetonitrile A; S2: enabling aminoacetonitrile A and cyanate to react, thus obtaining a reaction system b in which a product is cyanomethylurea B; S3: performing condensation-rearrangement on cyanomethylurea B and glyoxylic acid in an alkaline solution to obtain orotic acid I. The method has the advantages of safe operation, low cost, lesspollution from three wastes, total reaction yield of 80% or above, and easy industrialization.

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