889461-58-9 Usage
Molecular weight
186.21 g/mol
Structure
Cyclopropane ring with two ester groups attached to the 1 and 2 positions, and two ethyl groups attached to the ester groups
Chirality
Chiral compound with (1R,2R)configuration
Functional groups
Ester groups, cyclopropane ring, ethyl groups
Applications
Pharmaceutical and chemical research, synthesis of biologically active molecules, chiral drugs and pharmaceuticals
Properties
Unique properties due to cyclopropane ring structure, valuable building block for organic synthesis
Usage
Starting material for synthesis of complex organic molecules, key component in drug development
Solubility
Soluble in organic solvents like ethanol, methanol, and dichloromethane
Stability
Stable under normal conditions, but sensitive to heat, light, and moisture
Reactivity
Can undergo hydrolysis, esterification, and other reactions involving ester groups and cyclopropane ring
Hazards
May cause irritation to eyes, skin, and respiratory system; harmful if swallowed or inhaled
Storage
Store in a cool, dry, and well-ventilated area, away from heat and light sources, and in a sealed container
Regulatory status
May be subject to specific regulations depending on the intended use and location (e.g., pharmaceutical, chemical, or environmental regulations)
Check Digit Verification of cas no
The CAS Registry Mumber 889461-58-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,4,6 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 889461-58:
(8*8)+(7*8)+(6*9)+(5*4)+(4*6)+(3*1)+(2*5)+(1*8)=239
239 % 10 = 9
So 889461-58-9 is a valid CAS Registry Number.
889461-58-9Relevant academic research and scientific papers
Highly stereoselective cyclopropanation of α,β-unsaturated carbonyl compounds with methyl (diazoacetoxy)acetate catalyzed by a chiral ruthenium(II) complex
Chanthamath, Soda,Takaki, Suguru,Shibatomi, Kazutaka,Iwasa, Seiji
, p. 5818 - 5821 (2013/07/11)
Tantalizing triangles: The title reaction gives bicarbonyl cyclopropane products that can lead to versatile intermediates with high yields and stereoselectivities. This system was also applied to the enantioselective total synthesis of spiro cyclopropane oxindole, an HIV-1 nonnucleoside reverse transcriptase inhibitor. Copyright
ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS
-
Page/Page column 9; 12, (2010/04/23)
Cobalt-catalyzed asymmetric cyclopropanation of electron-deficient olefins.
Cobalt-catalyzed asymmetric cyclopropanation of electron-deficient olefins
Chen, Ying,Ruppel, Joshua V.,Zhang, X. Peter
, p. 12074 - 12075 (2008/03/27)
The cobalt(II) complex of a D2-symmetric chiral porphyrin [Co(1)] is an effective catalyst for asymmetric cyclopropanation of electron-deficient olefins, including α,β-unsaturated esters, amides, ketones, and nitriles. Due to the absence of dimerization of diazo compounds, the catalytic reactions can be performed in one-pot protocol using olefins as the limiting reagent, forming the desired electrophilic cyclopropane derivatives in high yields and selectivities under mild conditions. In most cases, both excellent diastereo- and enantioselectivity were achieved. Copyright
