88958-14-9

Upstream product

• 3296-06-8 1-azido-3-chlorobenzene 
• 141-97-9 ethyl acetoacetate 
• 108-42-9 3-chloro-aniline 

Downstream Products

• 88958-22-9 C₁₀H₇Cl₂N₃O 

Relevant academic research and scientific papers

Design, synthesis and biological studies of some new imidazole-1,2,3-triazole hybrid derivatives

Some new 4-((1H-imidazol-1-yl)diarylmethyl)-5-methyl-1-aryl-1H-1,2,3-triazoles 7a-i were designed and synthesized by the one-pot reaction of diaryl-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)methanol compounds with 1H-imidazole. The new compounds 7a-i were ch

WNT SIGNALING PATHWAY INHIBITORS FOR TREATMENTS OF DISEASE

Compounds and compositions are provided as inhibitors of the Wnt/β-catenin pathway for the treatment of diseases that implicate the same.

Convenient and efficient synthesis of disubstituted piperazine derivatives by catalyst-free, atom-economical and tricomponent domino reactions

One-pot, atom-economical, catalyst-free and tri-component domino reactions are applied to the diversity-oriented synthesis (DOS) of disubstituted piperazine derivatives under mild conditions with moderate to high yields. This protocol exhibits potential a

The synthesis of some new (S)-1-aryl-N-(1-hydroxy-3-phenylpropan-2-yl)-5- methyl-1H-1,2,3-triazole-4-carboxamide

Some new (S)-1-aryl-N-(1-hydroxy-3-phenylpropan-2-yl)-5-methyl-1 H-1,2,3-triazole-4-carboxamides 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i, 4j have been synthesized and established by 1H and 13C NMR, IR, MS spectra, CHN analyses, and x-ray

Synthesis and characterization of some new 1,2,4-triazines containing 1,2,3-triazole

A series of 3-(1 -aryl-1 H-1,2,3-triazol-4-yl)-6-phenyl-1,2,4-triazines were synthesized by the reaction of 1-aryl-1tf-1,2,3-triazole-4-carbohydrazide with 2-bromo-1- phenylethanone and sodium acetate in refluxed EtOH and AcOH. Their structures were chara

Synthesis of some novel 3,6-bis(1,2,3-triazolyl)-s-triazolo[3,4-b]-1,3,4- thiadiazole derivatives

The cyclization of 1-amino-2-mercapto-5-[1-(4-ethoxyphenyl)-5-methyl-1,2,3- triazol-4-yl]-1,3,4-triazole which was synthesized from p-ethoxyaniline with various triazole acid in absolute phosphorus oxychloride yields 3,6-bis(1,2,3-triazolyl)-s-triazolo[3,

Studies on condensed heterocyclic compounds: Part XVIII-synthesis of 6- (1-aryl-5-methyl-1, 2, 3-triazol-4-yl)-3-(4-pyridyl)-s-triazolo[3,4-b]-1. 3, 4-thiadiazoles

Several new 6-(1-aryl-5-methyl-1, 2, 3-triazol-4-yl)-3-(4-pyridyl)-s- triazolo[3,4-b]-1, 3, 4-thiadiazoles 3a-j have been synthesized by the condensation of 4-amino-5-mercapto-3-(4-pyridyl)-1, 2, 4-triazole2 with 1- aryl-4-carboxy-5-methyl-1, 2, 3-triazoles 1a-j in the presence of phosphorus oxychloride. The structures of the products obtained are characterized by elemental analyses and spectral data and the fragmentation pattern of the mass spectra of 3a-j is discussed. 3a-j have been screened for their antibacterial activity against B. subtilis and E. coli.

1H and 13C NMR - Spectroscopy of substituted 1,2,3-triazoles

1-Aryl-4-carboxy-5-methyl-1,2,3-triazoles were prepared by the condensation of aryl azides with ethyl acetoacetate. The structures of these compounds were characterized by MS, IR and 1H and 13C NMR spectroscopy. The measured and calc