88965-95-1Relevant academic research and scientific papers
Rearrangement of (1,2,4-triazol-4-yl) ethanols to (1,2,4-triazol-1-yl)ethanols
Bentley, T. William,Howle, Lisa M.,Wareham, Peter J.,Jones, Ray V. H.
, p. 7869 - 7878 (2007/10/02)
The mechanism of rearrangement of β-hydroxyethyl-(1,2,4-triazoles) has been shown using crossover experiments to be intermolecular and free energy profiles show that reactions are thermodynamically-controlled.
A GENERAL ANIONIC MECHANISM FOR THERMODYNAMIC CONTROL OF REGIOSELECTIVITY IN N-ALKYLATION AND ACYLATION OF HETEROCYCLES
Bentley, T. William,Jones, Ray V.H.,Wareham, Peter J.
, p. 4013 - 4016 (2007/10/02)
Regioselective alkylation of 1,2,4-triazole (Ia,IIa) to 1-alkyl derivatives (Ib) may occur by nucleophilic displacement of the triazole anion, is thermodynamically-controlled (shown by a free energy diagram), and the position of equilibrium is relatively
