88967-40-2Relevant academic research and scientific papers
X=Y-ZH SYSTEMS AS POTENTIAL 1,3-DIPOLES. PART 14. BRONSTED AND LEWIS ACID CATALYSIS OF CYCLOADDITIONS OF ARYLIDENE IMINES OF α-AMINO ACID ESTERS
Grigg, Ronald,Gunaratne, H. Q. Nimal,Sridharan, Visuvanathar
, p. 5887 - 5898 (2007/10/02)
Cycloadditions of arylidene imines of α-amino acid esters to a range of dipolarophiles show substantial rate enhancements in the presence of Bronsted and Lewis acids.For Bronsted acids the rate is related to the pKa of the acid and cycloadditio
X=Y-ZH Systems as Potential 1,3-Dipoles. Part 8. Pyrrolidines and Δ5-Pyrrolines (3,7-Diazabicyclooctenes) from the Reaction of Imines of α-Amino Acids and their Esters with Cyclic Dipolarophiles. Mechanism of Racemisation of α-Amino Acid
Amornraksa, Kitti,Grigg, Ronald,Gunaratne, H. Q. Nimal,Kemp, James,Sridharan, Visuvanathar
, p. 2285 - 2296 (2007/10/02)
Imines of α-amino acid esters with aromatic, heterocyclic, and aliphatic aldehydes generate azomethine ylides stereospecifically by a prototropic shift on heating in toluene.The azomethine ylides undergo cycloaddition to N-phenylmaleimide, maleic anhydrid
THE MECHANISM OF THE RACEMISATION OF α-AMINO ACIDS IN THE PRESENCE OF ALDEHYDES
Grigg, R.,Gunaratne, H.Q.N.
, p. 4457 - 4460 (2007/10/02)
Heating optically active α-amino acids in the presence of arylaldehydes effects racemisation via stereospecific formation of 1,3-dipolar species from the intermediate imines.These 1,3-dipoles can be trapped as their stetreospecific cycloadducts with N-phenylmaleimide.
