889673-50-1Relevant academic research and scientific papers
HETEROCYCLIC HYDROXAMIC ACIDS AS PROTEIN DEACETYLASE INHIBITORS AND DUAL PROTEIN DEACETYLASE-PROTEIN KINASE INHIBITORS AND METHODS OF USE THEREOF
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Paragraph 00303; 00304, (2016/04/26)
The present invention relates to novel hydroxamic acids which are specific histone deacetylase (HDAC) inhibitors and/or TTK/Mpsl kinase inhibitors, including pharmaceutically acceptable salts thereof, which are useful for modulating HDAC and/or TTK/Mpsl k
2,6-Disubstituted and 2,6,8-trisubstituted purines as adenosine receptor antagonists
Chang, Lisa C. W.,Spanjersberg, Ronald F.,Von Frijtag Drabbe Künzel, Jacobien K.,Mulder-Krieger, Thea,Brussee, Johannes,Ijzerman, Adriaan P.
, p. 2861 - 2867 (2007/10/03)
Purines have long been exploited as adenosine receptor antagonists. The substitution pattern about the purine ring has been well investigated, and certain criteria have become almost a prerequisite for good affinity at the adenosine A1 receptor
