88971-40-8

Basic information

• Product Name: BOC-L-DPA(BOC)-OH
• Synonyms: RARECHEM EM WB 0105;L-ALANINE, N-[(1,1-DIMETHYLETHOXY)CARBONYL]-3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-;BOC-L-DPA(BOC)-OH;Boc-L-Dap(Boc)-OH;3-N-Boc-amino-N-Boc-L-alanine;Boc-Dap(Boc)-OH
• CAS NO: 88971-40-8
• Molecular Formula: C₁₃H₂₄N₂O₆
• Molecular Weight: 304.34
• Mol File: 88971-40-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BOC-L-DPA(BOC)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-L-DPA(BOC)-OH(88971-40-8)
• EPA Substance Registry System: BOC-L-DPA(BOC)-OH(88971-40-8)

Safety Data

• Hazardous Substances Data: 88971-40-8(Hazardous Substances Data)

Usage

General Description

BOC-L-DPA(BOC)-OH, also known as t-butoxycarbonyl-L-phenylalanine(BOC)-OH, is a type of amino acid derivative. It is a white crystalline solid that is often used in organic synthesis and peptide chemistry. BOC-L-DPA(BOC)-OH is commonly employed as a building block for the preparation of various peptides and peptidomimetics. The BOC group serves as a protective group for the amino acid, allowing for selective deprotection and functionalization of specific functional groups during peptide synthesis. BOC-L-DPA(BOC)-OH has diverse applications in medicinal chemistry and drug discovery, particularly in the development of peptide-based therapeutics and pharmaceuticals.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1482-97-9 (S)-2,3-diaminopropanoic acid hydrochloride 
• 201472-68-6 Boc-Dpr(Boc)-OH*DCHA 
• 76387-70-7 (S)-3-amino-2-tert-butoxycarbonylaminopropionic acid 
• 515-94-6 (S)-2,3-diaminopropionic acid 

Downstream Products

• 1050584-36-5 C₅₂H₈₆N₈O₁₄ 

Relevant articles and documents

A template-directed synthetic approach to halogen-bridged mixed-valence platinum complexes on artificial peptides in solution

A template-directed synthetic approach to halogen-bridged mixed-valence platinum complexes has been performed in organic media using, for instance, a synthetic peptide bearing two bis(ethylenediamine)-based Pt(iv) complexes with two axial bromide anionic ligands, [1a(Pt(iv)Br2(en)) 2](RSO3)4, and a [Pt(ii)(en) 2](RSO3)2 complex (R = (C12H 25OCH2)2CHO(CH2)3-). The Royal Society of Chemistry.

Synthesis and nematicidal activity of piperazinedione derivatives based on the natural product Barettin

Nematodes are serious constraints of crop production worldwide. However, the traditional nematicides suffer from the side-effects, including environmental and human toxicity. Herein, more than 70 novel piperazinedione derivatives based on the natural product Barettin were synthesized and evaluated against the root-knot nematode Meloidogyne incognita (M. incognita). While most of synthesized compounds exhibited certain nematicidal activity at high concentration, the best one showed a nematicidal activity of 75% at 2.4 μmol/L.

Relationship between Taste and Structure of O-Aminoacyl Sugars Containing Basic Amino Acids

To study the relationship between taste and structure of O-aminoacyl sugars, a number of O-aminoacyl sugars containing basic amino acids were prepared.Taste quality of O-aminoacyl sugars was dependent on the side chain length of basic amino acids that were introduced into sugars.O-Aminoacyl sugars had an excellent sodium ion diet effect that could reduce sodium ion intake to 10 percent.