88973-09-5 Usage
Purpose
Used as a hypocholesterolemic agent.
Classification
Lipid-lowering drug.
Mechanism
Inhibits the enzyme squalene synthase.
Involvement in biosynthesis
Cholesterol.
Potential benefit
Reducing LDL cholesterol levels.
Clinical trials
Shown promise.
Unique structure
Dihydroquinoline core, substituted thiomorpholine ring, and a methylsulfanyl group.
Treatment potential
Hypercholesterolemia.
Contribution
May lead to the development of new cholesterol-lowering medications.
Check Digit Verification of cas no
The CAS Registry Mumber 88973-09-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,9,7 and 3 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 88973-09:
(7*8)+(6*8)+(5*9)+(4*7)+(3*3)+(2*0)+(1*9)=195
195 % 10 = 5
So 88973-09-5 is a valid CAS Registry Number.
88973-09-5Relevant academic research and scientific papers
Synthesis and antileukemic activity of 2-(2-methylthio-2-aminovinyl)-1-methylquinolinium iodides
Foye,Kim,Kauffman
, p. 1356 - 1358 (2007/10/02)
Reaction of 2-bis(2-methylthio)vinyl-1-methylquinolinium iodide with several heterocyclic aliphatic amines at 30-70° resulted in replacement of one methylthio group to give the title compounds. Reaction with pyrrolidine gave an unidentified product lackin