889865-47-8

Basic information

• Product Name: 4-Iodo-1-methylpyridin-2(1H)-one
• Synonyms: 4-Iodo-1-methylpyridin-2(1H)-one;4-iodo-1-methyl-2(1H)-Pyridinone;4-Iodo-1-methyl-1H-pyridin-2-one;4-Iodo-1-methyl-1,2-dihydropyridin-2-one
• CAS NO: 889865-47-8
• Molecular Formula: C₆H₆INO
• Molecular Weight: 235.02241
• Mol File: 889865-47-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4-Iodo-1-methylpyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Iodo-1-methylpyridin-2(1H)-one(889865-47-8)
• EPA Substance Registry System: 4-Iodo-1-methylpyridin-2(1H)-one(889865-47-8)

Safety Data

• Hazardous Substances Data: 889865-47-8(Hazardous Substances Data)

Usage

Description

4-Iodo-1-methylpyridin-2(1H)-one is a heterocyclic compound characterized by its molecular formula C6H6INO. It is distinguished by the presence of an iodo group, which endows it with unique structural properties and makes it a valuable reagent in organic synthesis. This chemical is known for its potential in the synthesis of pharmaceutical compounds and agrochemicals, as well as for its antibacterial and anti-inflammatory activities, positioning it as a promising candidate for drug development.

Uses

Used in Pharmaceutical Synthesis:
4-Iodo-1-methylpyridin-2(1H)-one is used as a key intermediate in the synthesis of pharmaceutical compounds due to its ability to facilitate the formation of carbon-carbon and carbon-heteroatom bonds. Its unique structural properties make it a versatile building block for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 4-Iodo-1-methylpyridin-2(1H)-one is utilized as a precursor in the synthesis of various agrochemicals. Its structural features contribute to the creation of effective compounds for agricultural applications, such as pesticides and herbicides.
Used in Organic Synthesis:
4-Iodo-1-methylpyridin-2(1H)-one is employed as a reagent in organic synthesis for its capacity to form essential chemical bonds. Its presence in reactions can lead to the production of complex organic molecules, showcasing its importance in the broader field of chemistry.
Used in Antibacterial and Anti-Inflammatory Drug Development:
4-Iodo-1-methylpyridin-2(1H)-one is used as a potential candidate for the development of new drugs with antibacterial and anti-inflammatory properties. Its inherent activities in these areas make it a valuable component in the creation of medications aimed at treating infections and inflammations.

Upstream product

• 858839-90-4 4-iodo-1,2-dihydropyridin-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 1160790-84-0 1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one 
• 1262298-40-7 6-(2-hydroxy-2-methylpropyl)-3-(2-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)propan-2-yl)-6-phenyl-1,3-oxazinan-2-one 
• 889865-39-8 4-{4-(2-tetrahydropyranyloxy)phenyl}-1-methyl-2(1H)-pyridone 
• 1193334-49-4 6-(3-hydroxy-3-methylbutyl)-6-isopropyl-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-1,3-oxazinan-2-one 
• 1193334-28-9 N-(2-methyl-1-((S)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-2-oxo-6-phenyl-1,3-oxazinan-6-yl)propan-2-yl)methanesulfonamide 
• 1193334-62-1 6-(3-hydroxypropyl)-6-isopropyl-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-1,3-oxazinan-2-one 
• 1193334-43-8 6-(3-hydroxypropyl)-6-isopropyl-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-1,3-oxazinan-2-one 
• 1193334-37-0 (6S)-6-(2-hydroxy-3-methoxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1193334-61-0 (6S)-6-(2-hydroxy-3-methoxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1193334-36-9 (6S)-6-(2,3-dihydroxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1193334-60-9 (6S)-6-(2,3-dihydroxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1193334-31-4 3-((R)-6-(4-fluorophenyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-2-oxo-1,3-oxazinan-6-yl)-2,2-dimethylpropanenitrile 
• 1114561-85-1 (S)-6-(2-hydroxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1151796-51-8 (S)-4-(2-hydroxy-2-methylpropyl)-1-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-4-phenyltetrahydropyrimidin-2(1H)-one 

Relevant articles and documents

NEW COMPOUNDS

The present invention provides certain compounds according to formula (I) which are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the specification.

GLYCINE TRANSPORTER INHIBITING SUBSTANCES

The present invention aims to provide novel compounds of formula [I] or pharmaceutically acceptable salts thereof that are based on a glycine uptake inhibiting action and which are useful in the prevention or treatment of such diseases as schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, posttraumatic stress disorder, specific phobia, acute stress disorder, etc.), depression, drug addiction, spasm, tremor, pain, and sleep disorder:

4, 6-DISUBSTITUTED 2-AMINO-PYRIMIDINES AS HISTAMINE H4 RECEPTOR MODULATORS

The present invention relates to substituted heterocyclic compounds of Formula (I) or pharmaceutically acceptable salts or N-oxides or quaternary ammonium salts thereof wherein constituent members are provided hereinwith, as well as their compositions and methods of use, which are histamine H4 receptor inhibitors/antagonists useful in the treatment of histamine H4 receptor-associated conditions or diseases or disorders including, for example, inflammatory diseases or disorders, pruritus, and pain.