889939-48-4 Usage
Uses
Used in Pharmaceutical Industry:
5-CHLORO-2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE is used as a reagent for the synthesis of various pharmaceutical compounds. Its ability to introduce the sulfonyl chloride group into other molecules makes it a valuable building block in the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, 5-CHLORO-2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE is used as a reagent for the synthesis of agrochemicals. Its sulfonyl chloride group can be incorporated into the molecular structure of various agrochemicals, enhancing their effectiveness and performance in agricultural applications.
Used in Materials Science:
5-CHLORO-2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE is also used in materials science for the synthesis of various materials with specific properties. Its sulfonyl chloride group can be used to create new materials with unique characteristics, such as improved stability, reactivity, or other desirable properties.
Safety Precautions:
Due to its reactivity and potential hazards, 5-CHLORO-2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE should be handled and used with caution in a laboratory setting. It is essential to follow proper safety protocols and use appropriate personal protective equipment to minimize the risk of exposure to this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 889939-48-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,9,3 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 889939-48:
(8*8)+(7*8)+(6*9)+(5*9)+(4*3)+(3*9)+(2*4)+(1*8)=274
274 % 10 = 4
So 889939-48-4 is a valid CAS Registry Number.
889939-48-4Relevant academic research and scientific papers
Preparation method of 5-halo-2-alkyloxy-4-toluene sulfochloride
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Paragraph 0055; 0058-0059, (2017/08/29)
The invention relates to the technical field of chemical material intermediate synthesis, in particular to a preparation method of 5-halo-2-alkyloxy-4-toluene sulfochloride. The 5-halo-2-alkyloxy-4-toluene sulfochloride is formed by taking cheap and avail
Synthesis and biological evaluation of some substituted-2-n-(5-chloro-2- methoxy-4-methylphenylsulphonyl) glutamic acid derivatives against prostate cancer cell line PC3
Hassan, Ghaneya Sayed,Rahman, Doaa Ezzat Abdel
, p. 212 - 221 (2013/03/28)
New series of substituted glutamine 5a-l and glutamic acid diamides, diureide and dihydrazide 7a-e were synthesized from parent glutamic acid compound 3 and evaluated for their cytotoxic activity against tumor cell line PC3 (prostate cancer cell line). Most of the tested compounds exploited potent growth inhibitory activity with IC50 values ranging 0.034-3.97 μm. Particularly, compounds 5a, 3, 5j, 5b, 7c, 7e, 5l, and 5k exhibited superior potency (IC50=0.034, 0.04, 0.05, 0.074, 0.25, 0.4, 0.49, 0.522 μm, respectively) to the reference drug Doxorubicin (IC50=0.63 μm), while compound 7b showed IC50, 0.71 μm, comparable to that of Doxorubicin. In summary, the newly synthesized compounds provided promising new lead for the future design and development of glutamine and glutamic acid derivatives as novel antitumor agents. The quantitative structure-activity relationship (QSAR) study was applied to find a mathematical correlation between the structures of compounds and their activity against PC3 cell line expressed as IC50 values.
