889940-20-9

Usage

Uses

Used in Pharmaceutical Industry:
4-Methyl-[1,8]naphthyridin-2-ol is used as a potential active pharmaceutical ingredient for its possible biological activities. The presence of the hydroxyl group allows for further chemical modifications, which can enhance its pharmacological properties, such as solubility, stability, and bioavailability. Its naphthyridine core may also contribute to specific binding affinities or interactions with biological targets, making it a candidate for the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Methyl-[1,8]naphthyridin-2-ol is used as a potential lead compound for the development of new pesticides or herbicides. Its unique structure may confer specific modes of action against pests or weeds, offering novel solutions to resistance issues in agriculture. Further research is required to explore its efficacy and safety in this context.
Further Research and Development:
4-Methyl-[1,8]naphthyridin-2-ol is used as a subject of research for understanding its full potential and exploring additional applications. Ongoing studies aim to elucidate its biological activities, mechanism of action, and potential side effects, which are crucial for its successful integration into various industries. 4-METHYL-[1,8]NAPHTHYRIDIN-2-OL's versatility and unique structure make it an interesting target for synthetic and medicinal chemists to investigate and innovate upon.

Upstream product

• 54231-33-3 3-bromo-2-nitropyridine 
• 1285387-84-9 tert-butyl 3-hydroxy-3-(2-pivalamidopyridin-3-yl)butanoate 
• 161987-58-2 1-(2-pivaloylaminopyridin-3-yl)ethanone 
• 86847-59-8 2-(pivaloylamino)pyridine 
• 504-29-0 2-aminopyridine 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 1285387-37-2 C₁₆H₁₃Cl₂N₅O 

Relevant academic research and scientific papers

Palladium-Catalyzed Ullmann Cross-Coupling of β-Iodoenones and β-Iodoacrylates with o-Halonitroarenes or o-Iodobenzonitriles and Reductive Cyclization of the Resulting Products to Give Diverse Heterocyclic Systems

The palladium-catalyzed Ullmann cross-coupling of β-iodoenones and β-iodoacrylates such as 5 (X = I) with o-halonitroarenes and o-iodobenzonitriles including 2 affords products such as compound 7. These can be engaged in a range of reductive cyclization r

Iodine- and indium(III) chloride-catalyzed facile syntheses of 1,5- and 1,8-naphthyridines

Iodine- and InCl3-catalyzed facile syntheses of 1,5- and 1,8-naphthyridines from 3-aminopyridine and 2-aminopyridines are described. The catalyst InCl3 could be recovered and reused up to five times efficiently.

CONDENSED RING PYRIDINE COMPOUNDS AS SUBTYPE-SELECTIVE MODULATORS OF SPHINGOSINE-1-PHOSPHATE-2 (S1P2) RECEPTORS

The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and or antagonist biological activity, wherein these compounds selected from the group consisting of wherein A, B, C, D, X, Y, Z and R3 are defined in the specification. Said compounds are useful for treating a disease or condition of a mammal selected from the group consisting of ocular diseases; systemic vascular barrier related diseases; allergies and other inflammatory diseases; cardiac diseases or conditions; fibrosis; pain and wounds.

An environmentally benign indium (III) chloride catalysed one-pot synthesis of quinolines

A convenient eco-friendly procedure for the quantitative synthesis of novel quinoline derivatives has been developed by a simple one-pot reaction of substituted anilines with P-ketoesters at 60°C in ethanol using recyclable indium chloride as catalyst. The reaction proceeds smoothly under solvent free conditions with quantitative yields.