89000-12-4 Usage
General Description
The chemical 2,4(1H,3H)-Pyrimidinedione, 5-[[(4-butoxyphenyl)thio]methyl]-, also known by its trade name Leflunomide, is a medication commonly used to treat rheumatoid arthritis. It works by inhibiting the activity of certain enzymes involved in the immune response, thereby reducing inflammation and joint damage. Leflunomide is classified as a disease-modifying antirheumatic drug (DMARD), meaning it can slow down the progression of the disease and improve the symptoms. However, it can also have potentially serious side effects, such as liver damage and decreased bone marrow function, and should be used with caution under the supervision of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 89000-12-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,0,0 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 89000-12:
(7*8)+(6*9)+(5*0)+(4*0)+(3*0)+(2*1)+(1*2)=114
114 % 10 = 4
So 89000-12-4 is a valid CAS Registry Number.
89000-12-4Relevant articles and documents
Uracil derivatives. IV. Growth-inhibitory activity against L-1210 cells of orotic acid derivatives and synthesis of 1-(β-D-ribofuranosyl)furo[3,4-d]pyrimidine-2,4,7(1H,3H,5H)-trione
Okada,Nakano,Miyake
, p. 3074 - 3083 (2007/10/02)
5-(Substituted thiomethyl)-6-carbamoyluracils (IIIb-h) and 5-(substituted thiomethyl)-uracils (Va-h) were prepared and their ability to inhibit the growth of L-1210 cells in vitro was examined. The reaction of silylated furo[3,4-d]pyrimidine-2,4,7(1H,3H,5
