89000-12-4 Usage
Uses
Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 5-[[(4-butoxyphenyl)thio]methyl]is used as a disease-modifying antirheumatic drug (DMARD) for the treatment of rheumatoid arthritis. It is employed to inhibit the activity of certain enzymes involved in the immune response, thereby reducing inflammation and joint damage, and slowing down the progression of the disease. However, its use should be carefully monitored due to the potential for serious side effects, such as liver damage and decreased bone marrow function.
Check Digit Verification of cas no
The CAS Registry Mumber 89000-12-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,0,0 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 89000-12:
(7*8)+(6*9)+(5*0)+(4*0)+(3*0)+(2*1)+(1*2)=114
114 % 10 = 4
So 89000-12-4 is a valid CAS Registry Number.
89000-12-4Relevant academic research and scientific papers
Uracil derivatives. IV. Growth-inhibitory activity against L-1210 cells of orotic acid derivatives and synthesis of 1-(β-D-ribofuranosyl)furo[3,4-d]pyrimidine-2,4,7(1H,3H,5H)-trione
Okada,Nakano,Miyake
, p. 3074 - 3083 (2007/10/02)
5-(Substituted thiomethyl)-6-carbamoyluracils (IIIb-h) and 5-(substituted thiomethyl)-uracils (Va-h) were prepared and their ability to inhibit the growth of L-1210 cells in vitro was examined. The reaction of silylated furo[3,4-d]pyrimidine-2,4,7(1H,3H,5
