890120-41-9

Upstream product

• 1074-88-0 1H-indole-7-carbaldehyde 
• 379669-79-1 3-hydroxy-4-phenyl-furan-2,5-dicarboxylic acid dimethyl ester 
• 408356-04-7 7-(3-hydroxypropyl)indole 
• 53996-10-4 3,4-dimethoxyfuran-2,5-dicarboxylic acid dimethyl ester 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 915377-06-9 3-methoxy-4-trifluoromethanesulfonyloxy-furan-2,5-dicarboxylic acid dimethyl ester 
• 890120-33-9 3-methoxy-4-phenyl-furan-2,5-dicarboxylic acid 
• 890120-31-7 3-methoxy-4-phenylfuran-2,5-dicarboxylic acid dimethyl ester 
• 890120-35-1 3-methoxy-4-phenyl-furan-2,5-dicarboxylic acid 5-methyl ester 
• 198220-22-3 3-hydroxy-4-methoxyfuran-2,5-dicarboxylic acid dimethyl ester 
• 890120-61-3 7-(3-acetoxypropyl)indole 
• 915377-39-8 methyl 3-(1H-indol-7-yl)propanoate 
• 104682-97-5 3-(1H-indol-7-yl)acrylic acid methyl ester 
• 890120-39-5 5-[7-(3-acetoxy-propyl)-1H-indole-3-carbonyl]-4-methoxy-3-phenyl-furan-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Regioselective synthesis of 3-aryl-5-(1H-indole-3-carbonyl)-4-hydroxyfuroic acids as potential insulin receptor activators

3-Methoxy-4-aryl-furan-2,5-dicarboxylic acid (8) is selectively converted into its C-5 methylester (6) by treatment with methyl chloroformate followed by decarboxylation in one flask. Acylation of the resulting half ester with a 7-substituted indole was p

4-Hydroxyfuroic acid derivatives

This invention relates to treating diabetes mellitus with certain 4-hydroxyfuroic acid derivatives. These derivates are of formula (I) below. Each variable is defined in the specification.