890131-90-5 Usage
General Description
N-Acetyl-2'-C-methyl-guanosine 2',3',5'-tribenzoate is a chemical compound that is a derivative of guanosine. It is formed by acetylating the amine group of guanosine at the 2'-position and methylating the sugar moiety at the C-2' position, followed by benzoate esterification at the 2', 3', and 5' positions. N-Acetyl-2'-C-methyl-guanosine 2',3',5'-tribenzoate has been investigated for its potential pharmacological properties, particularly as a potential antiviral agent. Its tribenzoate ester modification may enhance its bioavailability and stability, making it a potentially valuable compound for further study in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 890131-90-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,0,1,3 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 890131-90:
(8*8)+(7*9)+(6*0)+(5*1)+(4*3)+(3*1)+(2*9)+(1*0)=165
165 % 10 = 5
So 890131-90-5 is a valid CAS Registry Number.
890131-90-5Relevant articles and documents
The phosphoramidate ProTide approach greatly enhances the activity of β-2′-C-methylguanosine against hepatitis C virus
McGuigan, Christopher,Perrone, Plinio,Madela, Karolina,Neyts, Johan
scheme or table, p. 4316 - 4320 (2010/06/19)
β-2′-C-Methyl purines (1, 2) are known inhibitors of hepatitis C virus (HCV). We herein report the synthesis, biological and enzymatic evaluation of their 5′-phosphoramidate ProTides. Described herein are seven l-alanine phosphoramidate derivatives with v
