89024-98-6

Upstream product

• 67-56-1 methanol 
• 73731-37-0 Fmoc-Thr-OH 
• 186581-53-3 diazomethane 

Downstream Products

• 205441-95-8 (2R,3R)-2-(9-fluorenylmethoxycarbonylamino)-3-(4-methoxyphenyl)methoxybutanol 
• 205441-96-9 {(S)-2-(tert-Butyl-dimethyl-silanyloxy)-2-cyano-1-[(R)-1-(4-methoxy-benzyloxy)-ethyl]-ethyl}-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 205441-79-8 (3S,4R)-3-Amino-2-(tert-butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-pentanenitrile 
• 1332305-12-0 methyl N-(9-fluorenylmethoxycarbonyl)-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-L-threoninate 
• 1332305-18-6 methyl N-(9-fluorenylmethoxycarbonyl)-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-L-threoninate 
• 1332305-22-2 methyl N-(9-fluorenylmethoxycarbonyl)-O-[2,3,6-tri-O-benzoyl-4-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-β-D-glucopyranosyl]-L-threoninate 
• 160301-08-6 3-Iodomethyl-isochroman-1-one 
• 73731-37-0 Fmoc-Thr-OH 
• 1384895-11-7 methyl (R)-3-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyloxy)-(S)-2-(9-fluorenylmethoxycarbonylamino)butanoate 
• 1384895-10-6 methyl (R)-3-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyloxy)-(S)-2-(9-fluorenylmethoxycarbonylamino)butanoate 
• 395063-34-0 C₂₇H₂₇NO₇S 
• 327993-51-1 C₂₀H₁₈N₂O₇ 

Relevant academic research and scientific papers

Sterically Hindered 2,4,6-Tri- tert-butylpyridinium Salts as Single Hydrogen Bond Donors for Highly Stereoselective Glycosylation Reactions of Glycals

We demonstrate here that the strained and bulky protonated 2,4,6-tri-tert-butylpyridine salts serve as efficient catalysts for highly stereoselective glycosylations of various glycals. Moreover, the mechanism of action involves an interesting single hydrogen bond mediated protonation of glycals and not via the generally conceived Br?nsted acid pathway. The counteranions also play a role in the outcome of the reaction.

Synthesis of chlorophyll-amino acid conjugates as models for modification of proteins with chromo/fluorophores

A chlorophyll-a derivative bonded directly with epoxide at the peripheral position of the chlorin π-system was reacted with N-urethane and C-ester protected amino acids bearing an alcoholic or phenolic hydroxy group as well as a carboxy group at the residue to give chlorophyll-amino acid conjugates. The carboxy residues of N,C-protected aspartic and glutamic acids were esterified with the epoxide in high yields. The synthetic conjugates in dichloromethane had absorption bands throughout the visible region including intense red-side Qy and blue-side Soret bands. By their excitation at the visible bands, strong and efficient fluorescence emission was observed up to the near-infrared region. The chromo/fluorophores are promising for preparation of functional peptides and modification of proteins.

Mild and selective sodium azide mediated cleavage of p-nitrobenzoic esters.

[reaction: see text] A mild and selective cleavage of p-nitrobenzoic esters by sodium azide in methanol is reported. This new methodology is mild enough for use with acid- or base-sensitive compounds. No elimination byproducts are formed. Fmoc- and trifluoroacetyl-amino protecting groups, benzyl esters, and ethyl esters remain unaffected. Less reactive compounds are discussed in terms of steric factors, and yields are increased by altering the azide solvation.