89047-45-0 Usage
General Description
2-Quinolinecarboxylic acid hydrochloride, also known as quinaldic acid hydrochloride, is a chemical compound with the molecular formula C10H8ClNO2. It is a salt form of 2-quinolinecarboxylic acid, which is a derivative of quinoline. 2-Quinolinecarboxylic acid hydrochloride is commonly used in pharmaceutical research and drug development as a building block for the synthesis of various pharmacological agents. It has also been studied for its potential anti-inflammatory, antiviral, and antitumor properties. Additionally, 2-Quinolinecarboxylic acid hydrochloride is used in the production of dyes, pesticides, and other organic chemicals. However, it is important to handle this chemical with caution as it can be harmful if ingested or inhaled, and proper safety precautions should be followed when working with it.
Check Digit Verification of cas no
The CAS Registry Mumber 89047-45-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,0,4 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 89047-45:
(7*8)+(6*9)+(5*0)+(4*4)+(3*7)+(2*4)+(1*5)=160
160 % 10 = 0
So 89047-45-0 is a valid CAS Registry Number.
89047-45-0Relevant articles and documents
One-pot friedlnder quinoline synthesis: Scope and limitations
Li, An-Hu,Beard, David J.,Coate, Heather,Honda, Ayako,Kadalbajoo, Mridula,Kleinberg, Andrew,Laufer, Radoslaw,Mulvihill, Kristen M.,Nigro, Anthony,Rastogi, Pawan,Sherman, Dan,Siu, Kam W.,Steinig, Arno G.,Wang, Ti,Werner, Doug,Crew, Andrew P.,Mulvihill, Mark J.
experimental part, p. 1678 - 1686 (2010/06/22)
A highly effective one-pot Friedlnder quinoline synthesis from o-nitroarylcarbaldehydes and ketones or aldehydes was developed and the scope and limitations of the method were examined. The o-nitroarylcarbaldehydes were reduced to o-aminoarylcarbaldehydes with iron in the presence of a catalytic amount of aqueous hydrochloric acid; the amino compounds were then condensed in situ with ketones or aldehydes to form mono- or disubstituted quinolines, respectively, in good-to-excellent yields (58-100%). Georg Thieme Verlag Stuttgart - New York.
