890529-22-3Relevant articles and documents
Synthesis and evaluation of 2′-substituted cyclobutyl nucleosides and nucleotides as potential anti-HIV agents
Li, Yongfeng,Mao, Shuli,Hager, Michael W.,Becnel, Kimberlynne D.,Schinazi, Raymond F.,Liotta, Dennis C.
, p. 3398 - 3401 (2008/02/09)
A series of 2′-substituted cyclobutyl nucleoside analogs were efficiently prepared by constructing the core cyclobutyl ring using different [2+2] cycloaddition approaches. The triphosphate derivative of a cyclobutyl nucleoside was also synthesized and eva