89063-46-7

Upstream product

• 88981-65-1 (R_S)-p-tolylsulfinylacetic acid 
• 84960-67-8 cis-2,3,4,4a,5,6,7,11c-octahydro-5α-chloro-7-<(p-methoxyphenyl)-sulfonyl>-1H-pyrido<3,2-c>carbazole 
• 88981-61-7 2,2,2-trichloroethyl cis-2,3,4,4a,5,6,7,11c-octahydro-5α-chloro-7-<(p-methoxyphenyl)sulfonyl>-1H-pyrido<3,2-c>carbazole-1-carboxylate 
• 84960-65-6 (E)-1-<(p-methoxyphenyl)sulfonyl>-2-methyl-3-indole 
• 80664-26-2 N-<(4-methoxyphenyl)sulfonyl>-2-methylindole-3-carboxaldehyde 
• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 

Downstream Products

• 88981-69-5 (+)-2,3,4,5-tetradehydro-1-<(p-methoxyphenyl)sulfonyl>-11α-(prop-2-en-1-yl)-11β-(p-tolylthio)-20,21-dinoraspidospermidin-10-one 
• 88995-76-0 (+)-2,3,4,5-tetradehydro-1-<(p-methoxyphenyl)sulfonyl>-11α-methyl-11β-(p-tolylthio)-20,21-dinoraspidospermidin-10-one 
• 89016-48-8 (-)-2,3,4,5-tetradehydro-1-<(p-methoxyphenyl)sulfonyl>-11α-(p-tolylthio)-20,21-dinoraspidospermidin-10-one 
• 89016-47-7 (+)-2,3,4,5-tetradehydro-1-<(p-methoxyphenyl)sulfonyl>-11β-(p-tolylthio)-20,21-dinoraspidospermidin-10-one 

Relevant academic research and scientific papers

Total Synthesis of (-)-Kopsinilam, (-)-Kopsinine, and the Bis-indole Alkaloids (-)-Norpleiomutine and (-)-Pleiomutine

The racemic tetracyclic amine (5) was resolved and converted into (-)-kopsinine (16); subsequent coupling to (-)-eburnamine (2) gave (-)-norpleiomutine (4).

Synthesis of (+/-)-10,22-Dioxokopsane and (+/-)-Kopsanone, Heptacyclic Indole Alkaloids. Synthetic and Mechanistic Studies

The total synthesis of the heptacyclic indole alkaloids (+/-)-10,22-dioxokopsane (2) and (+/-)-kopsanone (3, X=O) is described.The imine 20 was condensed with β,β,β-trichloroethyl chloroformate to give the tetracyclic carbamate 21.Removal of the carbamate