89064-74-4

Basic information

• Product Name: (2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)methanol
• Synonyms: (2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)methanol
• CAS NO: 89064-74-4
• Molecular Weight: 554.683
• Mol File: 89064-74-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)methanol(89064-74-4)
• EPA Substance Registry System: (2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)methanol(89064-74-4)

Safety Data

• Hazardous Substances Data: 89064-74-4(Hazardous Substances Data)

Upstream product

• 917-54-4 methyllithium 
• 82598-88-7 2,3,4,6-tetra-O-benzyl-D-mannono-1,5-lactone 
• 97321-70-5 2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-β-D-manno-hept-1-enitol 
• 140397-47-3 2,6-anhydro-3,4,5,7-tetra-O-benzyl-aldehydo-D-glycero-D-galacto-heptopyranose 
• 1063747-88-5 1-(2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)formic acid 
• 89023-70-1 1-O-acetyl-3,4,5,7-tetra-O-benzyl-2-deoxy-2-nitro-β-D-manno-heptuolopyranose 
• 89023-69-8 1-O-acetyl-3,4,5,7-tetra-O-benzyl-2-deoxy-2-nitro-α-D-manno-heptuolopyranose 
• 89064-72-2 2,3,4,6-Tetra-O-benzyl-1-desoxy-1-nitro-D-mannopyranose 
• 89064-73-3 1-O-acetyl-2,6-anhydro-3,4,5,7-tetra-O-benzyl-D-galacto-heptitol 

Downstream Products

• 1063747-88-5 1-(2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)formic acid 
• 228115-93-3 1,7-(di-O-p-toluenesulfonyl)-3,4,5-tri-O-benzylmanno-2,6-anhydroheptitol 

Relevant articles and documents

Synthesis of β-C-Glycopyranosyl Aldehydes and 2,6-Anhydro-heptitols

A convenient route has been developed for the diastereoselective synthesis of β-C-glycopyranosyl aldehydes from d-glucose, d-mannose, and d-galactose. The key step in the synthesis of C-glycosyl aldehydes is the aryl driven reductive dehydration on 1-phen

TOLL-LIKE RECEPTOR 9 AGONISTS

The present invention provides TLR9 agonists comprising, as an active ingredient, a compound represented by formula (I): (wherein a represents 0 or 1; n represents an integer of 0 to 2; m represents an integer of 0 to 5; X1 and X2 each independently represent a hydrogen atom or hydroxy; Y represents an oxygen atom or a sulfur atom; -Q1-represents -O- or the like; -Q2- represents -O- or the like; -Z- represents -O- or the like; R1, R3 and R4 each independently represent hydroxy or the like; R2 and R5 each independently represent a hydrogen atom, hydroxy or the like; and A represents 6-aminopurin-9-yl or the like) or a pharmaceutically acceptable salt thereof, and the like.

Deoxy-nitrosugars. Stereoelectronic Control in the Reductive Denitration of Tertiary Nitro Ethers. A Synthesis of 'C-Glycosides'

The separate, radical denitration with Bu3SnH of the pyranose derivatives 3, 4, 9, and 10 gave in good yields exclusively the 'C-glycosides' 5 and 11, respectively (Scheme 1).Similar reduction of the cylohexyl derivatives 15, 16, 19 and 20 gave 4:1 mixtures of 17, 18, 21 and 22, respectively, always with predominant formation of an axial C,H-bond.In the furanose series a divergent behaviour was observed for the D-mannose-derived nitro ethers 25 and 27 and the D-ribose-derived nitro ethers 30 and 31, respectively, in that the former two gave isomerically homogeneous reduction products (26 and 28, respectively; Scheme 3) and the latter a 1:1 mixture of the diastereoisomers 32 and 33 (Scheme 4).The stereochemical results were explained on the basis of the stereoelectronic effect of the ring O-atom, the preferred conformation of the intermediate, pyramidal alkoxyalkyl radicals and steric effects in the trioxabicyclooctane ring system.