890709-77-0Relevant articles and documents
Dipeptide analogues containing 4-ethoxy-3-pyrrolin-2-ones
Hosseini, Masood,Kringelum, Henriette,Murray, Anthony,Tonder, Janne E.
, p. 2103 - 2106 (2007/10/03)
Pyrrolidine-2,4-diones (1) are naturally occurring analogues of amino acids. We herein present a facile synthesis of N-acylated, O-alkylated pyrrolin-2-ones (2) in high yield and excellent enantiopurity. Molecular mechanics calculations suggest that the r