89091-83-8

Basic information

• Product Name: 1-Pentanone, 2-(diphenylphosphinyl)-1-phenyl-
• CAS NO: 89091-83-8
• Molecular Formula: C23H23O2P
• Molecular Weight: 362.408
• Mol File: 89091-83-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Pentanone, 2-(diphenylphosphinyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentanone, 2-(diphenylphosphinyl)-1-phenyl-(89091-83-8)
• EPA Substance Registry System: 1-Pentanone, 2-(diphenylphosphinyl)-1-phenyl-(89091-83-8)

Safety Data

• Hazardous Substances Data: 89091-83-8(Hazardous Substances Data)

Upstream product

• 22949-84-4 butyl(triphenyl)phosphonium iodide 
• 93-89-0 benzoic acid ethyl ester 
• 4233-13-0 butyldiphenylphosphine oxide 

Downstream Products

• 16002-93-0 (E)-1-phenyl-1-pentene 
• 7642-18-4 (Z)-pent-1-en-1-ylbenzene 
• 88533-64-6 threo-2-diphenylphosphinoyl-1-phenylpentan-1-ol 
• 88533-64-6 erythro-2-diphenylphosphinoyl-1-phenylpentan-1-ol 
• 88533-64-6 2-(Diphenyl-phosphinoyl)-1-phenyl-pentan-1-ol 
• 88533-64-6 2-(Diphenyl-phosphinoyl)-1-phenyl-pentan-1-ol 

Relevant articles and documents

The Stereocontrolled Horner-Wittig Reaction: Synthesis of Disubstituted Alkenes

Addition of the lithium derivatives of phosphine oxides Ph2P(O)CH2R1 to aldehydes gives erythro adducts (11) with good stereoselectivity.Reduction of α-diphenylphosphinoyl ketones (12) gives threo adducts (11) with even better stereoselectivity.Purification by flash chromatography and/or crystallisation followed by elimination of Ph2PO2 gives pure Z- or E-alkenes with high material conversion.Explanations are offered for the stereoselectivities, conditions defined for full stereochemical control, and guidelines suggested for approaches to a given alkene.