890933-17-2

Upstream product

• 452-64-2 3,4-dimethyl-fluorobenzene 

Downstream Products

• 890933-20-7 2-chlorodifluoromethyl-4-fluorobenzal chloride 
• 858672-66-9 2-trifluoromethyl-4-fluorobenzal chloride 
• 890933-21-8 2-dichlorofluoromethyl-4-fluorobenzal chloride 
• 890933-18-3 2-chlorofluoromethyl-5-fluorobenzotrifluoride 
• 852462-70-5 2-trifluoromethyl-5-fluorobenzal chloride 
• 890933-19-4 2-chlorodifluoromethyl-5-fluorobenzal chloride 
• 90381-02-5 2-chlorofluoromethyl-4-fluorobenzotrifluoride 

Relevant academic research and scientific papers

FLUORINE-CONTAINING BENZAL CHLORIDE AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide 2-trifluoromethyl-5-fluorobenzal chloride and 2-trifluoromethyl-4-fluorobenzal chloride useful as a medicinal or an agrochemical intermediate, etc., and a method for producing them. SOLUTION: The 2-trifluoromethyl-5-fluorobenzal chloride is obtained by chlorinating 3,4-dimethylfluorobenzene with chlorine (Cl2) to obtain an isomer mixture (chlorination reaction mixture) of 2-trichloromethyl-5-fluorobenzal chloride and 2-trichloromethyl-4-fluorobenzal chloride, bringing the obtained isomer mixture in contact with hydrogen fluoride (HF) to obtain the fluorination reaction mixture, distilling the fluorination reaction mixture to be able to isolate 2-trifluoromethyl-5-fluorobenzal chloride. On the one hand, by reacting the distillation residue with HF under a condition for accelerating the reaction or for a longer period, 2-trifluoromethyl-4-fluorobenzal chloride is obtained.