891005-41-7

Basic information

• Product Name: 4-(4-bromophenyl)-1-[(1-methylpyrrol-2-yl)acetyl]semicarbazide
• Synonyms: 4-(4-bromophenyl)-1-[(1-methylpyrrol-2-yl)acetyl]semicarbazide
• CAS NO: 891005-41-7
• Molecular Weight: 351.203
• Mol File: 891005-41-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-(4-bromophenyl)-1-[(1-methylpyrrol-2-yl)acetyl]semicarbazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-bromophenyl)-1-[(1-methylpyrrol-2-yl)acetyl]semicarbazide(891005-41-7)
• EPA Substance Registry System: 4-(4-bromophenyl)-1-[(1-methylpyrrol-2-yl)acetyl]semicarbazide(891005-41-7)

Safety Data

• Hazardous Substances Data: 891005-41-7(Hazardous Substances Data)

Upstream product

• 158144-17-3 (1-methyl-pyrrol-2-yl)acetic acid hydrazide 
• 2493-02-9 4-bromophenyl isocyanate 
• 49669-45-6 ethyl (1-methyl-1H-pyrrol-2-yl)acetate 

Downstream Products

• 1217115-30-4 4-bromophenyl-3-[(1-methylpyrrol-2-yl)methyl]-4,5-dihydro-1,2,4-triazolin-5-one 

Relevant articles and documents

Anticancer screening and structure activity relationship study of some semicarbazides and 1,2,4-Triazolin-5-ones

In this paper some semicarbazide and 1,2,4-triazolin-5-one derivatives are evaluated in vitro for their anticancer activity towards human tumour cell line: ovary (TOV 112D), lung (A 549), breast (T47D) and uterus (Hela). Compounds 2-4 have been found to s

Synthesis, experimental and theoretical study on the structure of some semicarbazides with potential antibacterial activity

A series of 1,4-disubstituted semicarbazide and 4,4'-bis[1-substituted semicarbazide]diphenyl-methane derivatives were synthesized to explore their antibacterial activity. New compounds were characterized by elemental analysis and spectroscopic data. In order to find the tautomeric equilibrium for the molecules energy calculations for each possible tautomeric form of model compound 2, and for the most antibacterially active compound 7 in the investigated series, were calculated for the gas phase at the RHF/SCF/6-31G** level of theory.

Determination of the lipophilicity of some new derivatives of semicarbazide and 1,2,4-Triazol-5-one with potential antibacterial activity

The chromatographic behavior of new derivatives of 1,2,4-triazol-5-one and semicarbazide was determined. The lipophilicity was confirmed by the use of a RP-TLC method. The partition coefficients were calculated by use of theoretical procedures. The correl