89104-84-7Relevant academic research and scientific papers
Target Specific Tactics in Olefin Metathesis: Synthetic Approach to cis-syn-cis-Triquinanes and -Propellanes
Kotha, Sambasivarao,Aswar, Vikas R.
, p. 1808 - 1811 (2016)
A concise and simple synthetic approach to cis-syn-cis-triquinanes and -propellanes has been demonstrated via olefin metathesis starting with exo-nadic anhydride. This approach involves a ring-opening and ring-closing metathesis sequence of norbornene derivatives using Grubb's catalyst. Early-stage diallylation of norbornene derivatives is demonstrated followed by ring-closing metathesis that delivers propellanes exclusively. Surprisingly, ring-opening metathesis, late-stage diallylation, followed by ring-closing metathesis delivers triquinane as well as propellane derivatives.
Mechanochemical Grinding Diels-Alder Reaction: Highly Efficient and Rapid Access to Bi-, Tri-, and Tetracyclic Systems
Agarwal, Jyoti,Rani, Rashmi,Peddinti, Rama Krishna
, p. 1336 - 1340 (2017/06/27)
Grinding of various electron-deficient dienophiles with diverse dienes in a pestle and mortar for 1-15 minutes afforded the corresponding Diels-Alder adducts in quantitative yields under catalyst-free and solvent-free conditions, without the necessity for
Synthesis and antidepressant-like action of stereoisomers of imidobenzenesulfonylaziridines in mice evaluated in the forced swimming test
Duarte, Filipe S.,Andrade, Evilazio da S.,Vieira, Ricardo A.,Uieara, Marina,Nunes, Ricardo J.,de Lima, Thereza C.M.
, p. 5397 - 5401 (2008/02/07)
The present study describes the chemical synthesis and pharmacological evaluation of a new series of eleven compounds stereoisomers of imidobenzenesulfonylaziridines in the forced-swimming test (FST) in mice. The pharmacological results of these compounds
Synthesis and characterization of exo-endo and endo-endo benzenesulfonylaziridines
Da Silva Andrade, Evilazio,Nunes, Ricardo Jose,Uieara, Marina
, p. 3073 - 3081 (2007/10/03)
In the search for structural cyclic imide analogues of therapeutic interest, the synthesis, separation, and characterization of exo-endo 3 and endo-endo 4 stereoisomers of benzenesulfonylaziridines, not found in the literature, are described in this study
