Organic Letters
Letter
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outcome of the end product structure. We believe that
demonstration of this strategy adds a new tactic in designing
polycyclic and propellanes in a diversity-oriented18 manner. We
have also synthesized 15 stereochemically diverse propellane
derivatives, which is not possible by conventional routes. Since
the nonflattened three-dimensional17 molecular shape is
implicated in medicinal chemistry, our results are of interest
in drug design.
ASSOCIATED CONTENT
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S
* Supporting Information
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The Supporting Information is available free of charge on the
Experimental procedures, spectral data of new com-
pounds, and structures of catalysts used in screening in
AUTHOR INFORMATION
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Corresponding Author
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
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S.K. thanks the DST (New Delhi) for the award of a J. C. Bose
fellowship. We are also thankful to SAIF (IIT Bombay) for
providing the spectral data. V.R.A. thanks the CSIR-New Delhi
for the award of a research fellowship. We thank Ms. Sreevani
G. and Mr. Darshan Mhatre, Department of Chemistry, IIT
Bombay, for collecting crystal data. We thank Omega Cat
System for providing samples of M7-SIMes series catalysts.
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̀
(16) (a) Nguyen, N. N. M.; Leclere, M.; Stogaitis, N.; Fallis, A. G.
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