89113-96-2Relevant academic research and scientific papers
Formal Total Synthesis of (+/-)-Pseudomonic Acids from Dihydropyran
Jackson, Richard F. W.,Raphael, Ralf A.,Stibbard, John H. A,Tidbury, Raymond C.
, p. 2159 - 2164 (2007/10/02)
A new, convenient, and stereoselective route to a central intermediate in pseudomonic acid synthesis via the cis-fused γ-lactone, 2,7-dioxabicyclonon-4-en-8-one (3), is described.The required relative stereochemistry of the 2- and 5-side chains is established by a palladium(0)-mediated allylic substitution of the γ-lactone (3) by di-t-butylsodiomalonate.
ALKENE CARBOSULPHENYLATION AND CARBOSELENYLATION: THE USE OF ALLYLTRIMETHYLSILANE AND O-SILYLATED ENOLATES.
Alexander, Rikki P.,Paterson, Ian
, p. 5911 - 5914 (2007/10/02)
Allyltrimethylsilane, as well as O-silylated enolates, can be alkylated by the PhSCl adducts of alkenes and vinyl ethers (1, X=SPh); the PhSeCl analogues (1, X=SePh), however, are less useful for alkylation purposes due to competing nucleophilic attack at selenium.
