891182-95-9Relevant academic research and scientific papers
Synthesis of all stereoisomers of 3,3′-dimethoxy-7,7′- epoxylignane-4,4′-diol and their plant growth inhibitory activity
Nishiwaki, Hisashi,Nakayama, Kumiko,Shuto, Yoshihiro,Yamauchi, Satoshi
, p. 651 - 659 (2014/02/14)
All stereoisomers of 3,3′-dimethoxy-7,7′-epoxylignane-4, 4′-diol were synthesized to examine the effect of stereochemistry on their plant growth inhibitory activity using lettuce and Italian ryegrass. The effect of structural modifications such as dehydro
Synthesis of all stereoisomers of 3,3-Dimethoxy-7,7-epoxylignane-4,4-diol and their plant growth inhibitory activity
Nishiwaki, Hisashi,Nakayama, Kumiko,Shuto, Yoshihiro,Yamauchi, Satoshi
, p. 651 - 659 (2015/04/22)
All stereoisomers of 3,3-dimethoxy-7,7-epoxylignane-4,4-diol were synthesized to examine the effect of stereochemistry on their plant growth inhibitory activity using lettuce and Italian ryegrass. The effect of structural modifications such as dehydroxyla
MANASSANTIN COMPOUNDS AND METHODS OF MAKING AND USING SAME
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Page/Page column 44-46, (2010/07/10)
Provided are manassantin compounds and methods of using the compounds. Provided are methods of treating a disease, the method comprising administering a compound according to Formula I. Further provided are pharmaceutical compositions comprising compounds
Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations
Kasper, Amanda C.,Moon, Eui Jung,Hu, Xiangqian,Park, Yongho,Wooten, Ceshea M.,Kim, Hyoungsu,Yang, Weitao,Dewhirst, Mark W.,Hong, Jiyong
scheme or table, p. 3783 - 3786 (2010/03/01)
We have shown that manassantin A downregulated the HIF-1α expression and inhibited the secretion of VEGF. We have also demonstrated that the 2,3-cis-3,4-trans-4,5-cis-configuration of the tetrahydrofuran is critical to the HIF-1 inhibition of manassantin
Stereoselective synthesis of tetrahydrofuran lignans via BF 3·OEt2-promoted reductive deoxygenation/ epimerization of cyclic hemiketal: Synthesis of (-)-odoratisol C, (-)-futokadsurin A, (-)-veraguensin, (+)-fragransin A2, (+)-galbel
Kim, Hyoungsu,Wooten, Ceshea M.,Park, Yongho,Hong, Jiyong
, p. 3965 - 3968 (2008/02/11)
A versatile route to the synthesis of 2,5-diaryl-3,4- dimethyltetrahydrofuran lignans, (-)-odoratisol C. (1), (-)-futokadsurin A (2), (-)-veraguensln (3), (+)-fragransin A2 (4), (+)-galbelgin (5), and (+)-talaumidin (6), is described. Central t
Total synthesis and stereochemical confirmation of 2,5-diaryl-3,4- dimethyltetrahydrofuran lignans: (+)-Fragransin A2, (+)-galbelgin, (+)-talaumidin, (-)-saucernetin and (-)-verrucosin
Hanessian, Stephen,Reddy, Gone Jayapal
, p. 475 - 479 (2008/01/01)
A new ring closure to tetrasubstituted tetrahydrofurans from the intramolecular attack of an OMOM ether onto a benzylic mesylate proceeds through a quinonoid intermediate or by direct SN2 displacement. The synthesis of diastereomeric biological
Effect of the benzylic structure of lignan on antioxidant activity
Yamauchi, Satoshi,Sugahara, Takuya,Matsugi, Junko,Someya, Tatsushi,Masuda, Toshiya,Kishida, Taro,Akiyama, Koichi,Maruyama, Masafumi
, p. 2283 - 2290 (2008/03/17)
The effect of the benzylic structure of lignan on antioxidant activity was evaluated. Secoisolariciresinol (1) and 3,4-bis(4-hydroxy-3-methoxybenzyl) tetrahydrofuran (2), which have two secondary benzylic positions without oxygen, showed the highest antioxidant activity. Optically active verrucosin (4) was synthesized for the first time in this experiment.
