89124-04-9

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-6-hydrazinylpyrimidin-2-amine is used as a key intermediate in the synthesis of various pharmaceuticals for its potential therapeutic applications.
Used in Antitumor Drug Development:
4-Chloro-6-hydrazinylpyrimidin-2-amine is used as a precursor in the development of potential antitumor drugs, targeting cancer cells and contributing to the discovery of novel cancer treatments.
Used in Antiviral Drug Synthesis:
4-Chloro-6-hydrazinylpyrimidin-2-amine is utilized as a building block in the synthesis of antiviral drugs, aiming to combat viral infections and develop new therapeutic agents.
Used in Tuberculosis Treatment Research:
4-Chloro-6-hydrazinylpyrimidin-2-amine is studied for its potential use in the treatment of tuberculosis, exploring its efficacy in targeting the causative agents of this disease.
Used in Organic Synthesis:
As a versatile building block, 4-Chloro-6-hydrazinylpyrimidin-2-amine is used in organic synthesis to create a variety of chemical compounds with diverse applications in research and industry.

InChI:InChI=1/C4H6ClN5/c5-2-1-3(10-7)9-4(6)8-2/h1H,7H2,(H3,6,8,9,10)

Upstream product

• 56-05-3 2-Amino-4,6-dichloropyrimidine 

Downstream Products

• 154989-15-8 4-Chloro-6-{N'-[1-(4-chloro-phenyl)-eth-(Z)-ylidene]-hydrazino}-pyrimidin-2-ylamine 
• 154989-17-0 4-Chloro-6-{N'-[1-(4-nitro-phenyl)-eth-(Z)-ylidene]-hydrazino}-pyrimidin-2-ylamine 
• 1306739-68-3 7-chloro-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 
• 154989-16-9 4-Chloro-6-{N'-[1-(4-methoxy-phenyl)-eth-(Z)-ylidene]-hydrazino}-pyrimidin-2-ylamine 

Relevant academic research and scientific papers

5-AMINO-8-(4-PYRIDYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-3-ONE COMPOUNDS FOR USE AGAINST CANCER

Described herein are triazalone compounds of Formula (I): and pharmaceutically acceptable salts thereof. Methods of making and using compounds of Formula (I) are also described. Compounds of Formula (I) and pharmaceutically acceptable salts thereof can be useful as adenosine receptor antagonists, for example in the treatment of diseases or conditions mediated by the adenosine receptor, such as cancer, movement disorders, or attention disorders.

5-AMINO-8-(4-PYRIDYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-3-ONE COMPOUNDS FOR USE AGAINST CANCER

Described herein are triazalone compounds of Formula (I) and pharmaceutically acceptable salts thereof. Methods of making and using compounds of Formula (I) are also described. Compounds of Formula (I) and pharmaceutically acceptable salts thereof can be

TRIAZOLONE COMPOUNDS

Described herein are triazalone compounds of Formula (I): and pharmaceutically acceptable salts thereof. Methods of making and using compounds of Formula (I) are also described. Compounds of Formula (I) and pharmaceutically acceptable salts thereof can be

CRYSTAL FORM AND SALT TYPE OF TRIAZOLOPYRIMIDINE COMPOUND AND PREPARATION METHOD THEREOF

Disclosed in the present invention are a crystal form of a [1,2,4]triazolo[1,5-c]pyrimidine compound and a preparation method thereof. Further disclosed is a use of the crystal form in the preparation of a medicament for treating A2A receptor r

Preparation method and intermediate of heteroaryl [4, 3-c] pyrimidine-5-amine compound

The invention relates to a preparation method and an intermediate of a heteroaryl [4, 3-c] pyrimidine-5-amine compound. Specifically, the present invention relates to a heteroaryl [4, 3-c] pyrimidine-5-amine compound or a preparation method of its salt. The method comprises the following steps: preparing a compound as shown in a formula II from a compound as shown in a formula III, and reacting the compound as shown in the formula II serving as a raw material to obtain a compound as shown in a formula I. In the reaction process, few impurities are generated, the purification process is simplified, and the preparation method is suitable for industrialization.