89143-07-7

Usage

Purpose

Used primarily as a local anesthetic in medical and dental procedures

Function

Temporarily numbs a specific area of the body and blocks the transmission of pain signals to the brain

Chemical class

Pyrrolidinones

Structural similarity

Similar to procaine, a widely used local anesthetic

Regulation

Has potential for abuse and is regulated in many countries.

Upstream product

• 4469-80-1 4-propoxyaniline 
• 106058-27-9 (Z)-3-(4-Propoxy-phenylcarbamoyl)-acrylic acid 

Downstream Products

• 106058-32-6 3-(4-Methoxy-phenylamino)-1-(4-propoxy-phenyl)-pyrrolidine-2,5-dione 
• 106058-42-8 3-(4-Ethoxy-phenylamino)-1-(4-propoxy-phenyl)-pyrrolidine-2,5-dione 
• 106058-54-2 3-(4-Phenylsulfanyl-phenylamino)-1-(4-propoxy-phenyl)-pyrrolidine-2,5-dione 
• 89143-29-3 3-Piperidin-1-yl-1-(4-propoxy-phenyl)-pyrrolidine-2,5-dione 
• 89143-17-9 1'-(4-Propoxy-phenyl)-[1,3']bipyrrolidinyl-2',5'-dione 

Relevant academic research and scientific papers

Synthesis of N-Aryl/heteroaryl/-substituted-methyl-&α-(p-substituted anilino)succinimides as Antituberculosis Agents

A series of N-Aryl/heteroaryl/substituted-methyl-α-(p-substituted anilino)succinimides (II) have been prepared and screened in vitro against H37Rv strain of Mycobacterium tuberculosis.Some of these compounds exhibit activity upto 0.39 μg/ml concentration.

Synthesis of N-Aryl/substituted-methyl/heteroaryl-&α-pyrrolidino/piperidino Succinimides as Antituberculosis Agents

A series of N-Aryl/substituted-methyl/heteroaryl-α-pyrrolidino- and piperidino-succinimides (II) have been prepared and screened in vitro against H37Rv strain of Mycobacterium tuberculosis.Some of these compounds exhibit activity upto 1.56 μg/ml concentration.