4469-80-1

Basic information

• Product Name: 4-PROPOXYANILINE
• Synonyms: AKOS BC-2570;AKOS BBB/084;4-PROPOXYANILINE;4-n-Propoxyaniline;4-propoxy-benzenamin;P-PROPOXYANILINE;TIMTEC-BB SBB008316;4-propoxyphenylamine
• CAS NO: 4469-80-1
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.21
• EINECS: 224-740-0
• Product Categories: Amines;C9 to C10;Nitrogen Compounds
• Mol File: 4469-80-1.mol
• Article Data: 31

Chemical Properties

• Melting Point: 265-267℃
• Boiling Point: 261.7±13.0℃ (760 Torr)
• Flash Point: >230 °F
• Appearance: Brown/Liquid
• Density: 1.016±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.0114mmHg at 25°C
• Refractive Index: 1.536
• Solubility: Slightly soluble (1.3 g/L at 25°C).
• PKA: 5.24±0.10(Predicted)
• CAS DataBase Reference: 4-PROPOXYANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PROPOXYANILINE(4469-80-1)
• EPA Substance Registry System: 4-PROPOXYANILINE(4469-80-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 4469-80-1(Hazardous Substances Data)

Usage

Uses

4-n-Propoxyaniline is used as a reactant for preparation of aggrecanase inhibitors.

InChI:InChI=1/C9H13NO/c1-2-7-11-9-5-3-8(10)4-6-9/h3-6H,2,7,10H2,1H3

Upstream product

• 71-23-8 propan-1-ol 
• 100-17-4 para-methoxynitrobenzene 
• 55792-12-6 (4-Propoxy-phenyl)-carbamic acid 2-piperidin-1-yl-ethyl ester; hydrochloride 
• 20367-32-2 4-propoxyacetanilide 
• 1568-66-7 1-allyloxy-4-nitrobenzene 
• 241147-96-6 2-(4-(tert-butyl)phenyl)benzo[d][1,3,2]dioxaborole 
• 1688-69-3 p-allyloxyaniline 
• 100-00-5 4-chlorobenzonitrile 
• 123-30-8 4-amino-phenol 
• 106-94-5 propyl bromide 
• 100-02-7 4-nitro-phenol 
• 1124-31-8 potassium 4-nitrophenolate 
• 103-90-2 4-acetaminophenol 
• 540-37-4 p-aminoiodobenzene 

Downstream Products

• 109090-41-7 4-propoxy-N-(2-[2]pyridyl-ethyl)-aniline 
• 108013-49-6 6-propoxy-2-[2]pyridyl-benzothiazole 
• 101112-27-0 pyridine-2-carbothioic acid-(4-propoxy-anilide) 
• 41240-81-7 2-chloro-N-(4-propoxy-phenyl)-acetamide 
• 100141-68-2 3-chloro-propionic acid-(4-propoxy-anilide) 
• 14921-37-0 4-propoxy-N-(4-propoxy-benzyliden)-aniline 
• 13910-53-7 3-(4-Propoxy-anilino)-propylamin 
• 33228-21-6 p-n-Butyl-p'-propyloxy-azobenzol 
• 87672-26-2 N-(4-Propoxy-phenyl)-pyridine-2-carboxamidine 
• 96722-54-2 C₁₂H₁₅ClN₂O₃ 
• 99009-58-2 6-chloro-3-nitro-2-[(4-propoxyphenyl)amino]benzoic acid 
• 76663-12-2 2-(4-Propoxy-phenylamino)-N-(4-sulfamoyl-phenyl)-acetamide 
• 70350-96-8 ethyl N-(4-propoxyphenyl)glycinate 
• 87739-50-2 6,6-Dimethyl-1-(4-propoxy-phenyl)-1,6-dihydro-[1,3,5]triazine-2,4-diamine; hydrochloride 

Relevant articles and documents

Liquid crystalline behaviour of polymer networks based on segmented chain mesogenic polymers

The synthesis of some crosslinked polymers based on a segmented-chain polymeric mesogen containing variable amounts of a side chain substituent is reported. The unswollen networks show thermotropic mesomorphism of nematic character whose stability decreases with increasing substitution and crosslink density. Depending on the same parameters, the swollen networks may show optical anisotropy at room temperature whose origin is attributed to phase separation.

Synthesis and mesomorphic properties of 2,4-bis(4′-n-pentyloxybenzoyloxy)- benzylidine-4″- n-alkoxyaniline

The synthesis and mesomorphic properties of a new series of 2,4-bis(4′-npentyloxybenzoyloxy)- benzylidine-4″ -n-alkoxyaniline (DC5An) are reported. The molecular structure of compounds was confirmed by FTIR, 1H-NMR, 13C-NMR, mass spectroscopy and elemental analysis. The mesomorphic properties were studied by differential scanning calorimetry (DSC) and polarizing optical microscopy (POM) measurements. All compounds of the series exhibit nematic (N) and smectic C (SmC) phases. The first four homologues (DC5A1-DC5A4) display a N mesophase, whereas the highest homologues (DC5A5-DC5A10) exhibit an enantiotropic dimorphism N and SmC phases. The mesomorphic properties of the present series are compared and discussed with other structurally related series.

Properties of liquid crystals and Cu2+ recognition based on Schiff bases

Two series of new Schiff base compounds were synthesized. For Schiff base compounds with a pyridine nitrogen atom in 4-position (7a-e), their supramolecular hydrogen bonding complexes show good liquid crystal properties. However, no liquid crystal property is observed for 8a-e. Results of theoretical calculations demonstrate that it is the intermolecular hydrogen bond of Schiff base compounds (8a-e) that prevents the formation of supramolecular hydrogen bonding. The Schiff base compounds, with terminal alkoxy chains, can recognize Cu2+ selectively with a color change. Nevertheless, others cannot recognize Cu2+.