89154-74-5Relevant academic research and scientific papers
Crystal structure of bis(O-isopropyldithiocarbonato)diphenyltin(IV)
Donoghue, Neil,Tiekink, Edward R. T.
, p. 179 - 184 (1991)
The crystal structure of the title compound, iPr)2>, shows the Sn atom to exist in a skew-trapezoidal planar geometry defined by two asymmetrically coordinated isopropylxanthate ligands (Sn-S(1) 2.482(1), Sn-S(2) 3.179(1) Angstroem and Sn-S(3) 2.500(1), Sn-S(4) 3.067(1) Angstroem) and two phenyl groups that lie over the weaker Sn-S interactions giving a C-Sn-C angle of 128.6(1) deg.
Synthesis, Spectroscopy, Semi-empirical and Biological Activities of Organotin(IV) Complexes with o-Isopropyl Carbonodithioic Acid
Javed, Fatima,Ali, Saqib,Shahzadi, Saira,Khalid, Nasir,Tabassum, Saira,Khan, Imran,Sharma, Saroj K.,Qanungo, Kushal
, p. 728 - 738 (2015/09/02)
New organotin(IV) complexes have been synthesized by treating potassium o-isopropyl carbonodithioate with R2SnCl2/R3SnCl in 1:2/1:1 M/L ratio. All complexes have been characterized by IR and NMR (1H, 13C) spectroscopy. IR results shows that ligand acts as bidentate which is also confirmed by semi-empirical study. NMR data reveals four coordinated geometry in solution. Computed positive heat of formation shows that complex 5 is thermodynamically unstable. UV/visible spectroscopy was used to assess the mode of interaction and binding of the complexes with DNA which shows that complex 5 exhibits higher binding constant as compared to complex 3. In protein kinase inhibition assay, compound 3 was found most active, while other biological activities shows that triorganotin(IV) complexes are biologically more active as compared to diorganotin(IV) complexes.
