89179-79-3

Upstream product

• 1004-96-2 3-methylisoxazole-5-carboxylic acid methyl ester 
• 63366-79-0 3-methylisoxazole-5-carboxylic acid ethyl ester 

Downstream Products

• 92547-99-4 3-methyl-isoxazole-5-carboxylic acid (1-methyl-3-phenyl-propylidene)-hydrazide 
• 95770-39-1 3-methyl-isoxazole-5-carboxylic acid phenethylidenehydrazide 
• 1085-33-2 3-methyl-isoxazole-5-carboxylic acid benzylidenehydrazide 
• 1087-08-7 3-methyl-isoxazole-5-carboxylic acid (1-phenyl-ethylidene)-hydrazide 
• 97809-93-3 3-methyl-isoxazole-5-carboxylic acid (1-methyl-2-phenyl-ethylidene)-hydrazide 
• 92968-54-2 5-methyl-isoxazole-3-carboxylic acid 2-methyl-5-phenyl-pyrrol-1-ylamide 
• 94460-19-2 3-methyl-isoxazole-5-carboxylic acid 2-methyl-5-phenyl-pyrrol-1-ylamide 
• 101670-70-6 3-methyl-isoxazole-5-carboxylic acid N'-(4-dimethylamino-benzyl)-hydrazide 
• 2532-35-6 3-methyl-isoxazole-5-carboxylic acid N'-(1-methyl-3-phenyl-propyl)-hydrazide 
• 1219-39-2 3-methyl-isoxazole-5-carboxylic acid N'-(1-phenyl-ethyl)-hydrazide 
• 2532-34-5 3-methyl-isoxazole-5-carboxylic acid N'-(1-methyl-2-phenyl-ethyl)-hydrazide 
• 2532-31-2 3-methyl-isoxazole-5-carboxylic acid N'-phenethyl-hydrazide 
• 1085-32-1 3-methyl-isoxazole-5-carboxylic acid N'-benzyl-hydrazide 

Relevant academic research and scientific papers

BENZODIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM

Compounds having the general formula (I) wherein R1, R2, R3, R4, R5 and X are as described herein, compositions including the compounds and methods of using the compounds.

HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS

Compounds of Formula (I) and Formula (II), pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.

Compounds Which Selectively Modulate The CB2 Receptor

Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.