89181-90-8

Usage

Physical state

Clear and colorless liquid

Odor

Pungent

Usage

Intermediate in the production of pharmaceuticals and agrochemicals

Chemical classification

Ester containing a tetrazole group

Potential

Explosive material

Application

Building block in organic synthesis

Importance

Valuable reagent in chemical research and development

Safety

Proper handling and storage procedures should be followed

Upstream product

• 15284-25-0 1-(2-hydroxyethyl)tetrazole 
• 108-24-7 acetic anhydride 
• 122-51-0 orthoformic acid triethyl ester 
• 1854-30-4 2-acetoxy-1-aminoethane 
• 20739-39-3 1-acetoxy-2-aminoethane hydrochloride 

Relevant academic research and scientific papers

Synthesis of funetionalized tetrazenes as energetic compounds

1,4-Bis[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]-1,4-dimethyl-2-tetrazene (12a), 1,4-bis[1-isopropoxycarbonylmethyl1H-tetrazol-5-yl]-1,4-dimethyl-2- tetrazene (12b), and 1,4-bis[1-carboxymethyl-1H-tetrazol-5yl]-1,4-dimethyl-2- tetrazene (13) have been synthes

Nitratoethyl-5H-tetrazoles: improving the oxygen balance through application of organic nitrates in energetic coordination compounds

1- and 2-Nitratoethyl-5H-tetrazole (1-NET and 2-NET) were prepared through nitration of the respective alkyl alcohol using 100% nitric acid. A mixture of 1- and 2-hydroxyethyl-5H-tetrazole was obtained after alkylation of 1,5H-tetrazole. Also, a one-pot s

HETEROCYCLIC DERIVATIVES

This invention relates to compounds of the general formula (I) STR1 and physiologically acceptable salts and hydrates thereof, in which R 1 represents a hydrogen atom or an alkyl, alkanoyl, aroyl or trifluoroalkyl group;R 2 represents a hydrogen atom or an alkyl or alkenyl group or C 2-6 alkyl group substituted by a hydroxy or alkoxy group;X represents a sulphur atom or NH;Y represents an oxygen or sulphur atom or a bond;m represents 1, 2 or 3; andn represents 2, 3 or 4. The compounds show pharmacological activity as selective histamine H 2-antagonists.

SYNTHESIS AND PROPERTIES OF 1-(2-HYDROXYETHYL)TETRAZOLE

The heterocyclization of monoethanolamine with ethyl orthoformate and sodium azide in acetic acid was studied.It was shown that the reaction proceeds through a step involving the formation of a disubstituted formamidine and leads to the production of 1-(2-hydroxyethyl)tetrazole in high yield.A method for the purification of 1-(2-hydroxyethyl)tetrazole by complexing with cupric chloride was developed, and its physicochemical properties and some chemical transformations were investigated.