1854-30-4 Usage
General Description
O-Acetylethanolamine, also known as N-acetyl ethanolamine or N-acetyl-2-aminoethanol, is a chemical compound with the formula C4H9NO2. It is an acetylated derivative of ethanolamine, a naturally occurring compound in the human body. O-Acetylethanolamine is a neurotransmitter and has been found to have neuroprotective properties, potentially offering therapeutic benefits in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. Additionally, it has been investigated for its anti-inflammatory and analgesic effects, suggesting potential applications in the management of pain and inflammation. O-Acetylethanolamine is also a precursor to the endocannabinoid anandamide, which plays a role in regulating mood, appetite, and pain perception. Overall, O-Acetylethanolamine is a compound of interest in the fields of neuroscience, pharmacology, and medicine due to its potential therapeutic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1854-30-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,5 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1854-30:
(6*1)+(5*8)+(4*5)+(3*4)+(2*3)+(1*0)=84
84 % 10 = 4
So 1854-30-4 is a valid CAS Registry Number.
1854-30-4Relevant articles and documents
Metal-Free O-Selective Direct Acylation of Amino Alcohols Through Pseudo-Intramolecular Process
Yokoyama, Soichi,Shibauchi, Hiroshi,Asahara, Haruyasu,Nishiwaki, Nagatoshi
, p. 1125 - 1133 (2019/02/01)
Efficient α-aryl-β-keto ester acylation of amine accompanied by the elimination of ethyl phenylacetate was achieved owing to the pseudo-intramolecular process. The eliminated ethyl phenylacetate could be recycled by conversion into an α-aryl-β-keto ester upon treatment with an acyl chloride in the presence of lithium bis(trimethylsilyl)amide, by which the atom economy considerably increased. Acylation using an α-aryl-β-keto ester is highly sensitive to the bulkiness of the nucleophile, which facilitated the regioselective-acylation of the less hindered amino group in diamine without protecting the other. The transacylation of α-aryl-β-keto ester with N-alkylamino alcohol resulted in chemoselective O-acylation without protecting the amino group because the hydroxy group was attracted to the reaction site of the keto ester by forming an ammonium salt. Transacylation was demonstrated to be a practically useful tool for organic synthesis because this protocol can be conducted under mild conditions with simple manipulations in the absence of any additives such as metal catalyst and base.
