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1-methylethyl 4-({[((1S)-1-({4-[(1,1-dimethylethyl)oxy]phenyl}methyl)-2-{[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]amino}-2-oxoethyl)amino]carbonyl}amino)benzoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

891845-35-5

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891845-35-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 891845-35-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,1,8,4 and 5 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 891845-35:
(8*8)+(7*9)+(6*1)+(5*8)+(4*4)+(3*5)+(2*3)+(1*5)=215
215 % 10 = 5
So 891845-35-5 is a valid CAS Registry Number.

891845-35-5Relevant academic research and scientific papers

Discovery of novel and long acting muscarinic acetylcholine receptor antagonists

Jin, Jian,Wang, Yonghui,Shi, Dongchuan,Wang, Feng,Davis, Roderick S.,Jin, Qi,Fu, Wei,Foley, James J.,Webb, Edward F.,Dehaas, Chris J.,Berlanga, Manuela,Burman, Miriam,Sarau, Henry M.,Morrow, Dwight M.,Rao, Parvathi,Kallal, Lorena A.,Moore, Michael L.,Rivero, Ralph A.,Palovich, Michael,Salmon, Michael,Belmonte, Kristen E.,Busch-Petersen, Jakob

supporting information; experimental part, p. 4866 - 4869 (2009/08/09)

High throughput screening and subsequent optimization led to the discovery of novel quaternary ammonium salts as highly potent muscarinic acetylcholine receptor antagonists with excellent selectivity. Compounds 8a, 13a, and 13b showed excellent inhibitory

QUATERNARY AMMONIUM SALTS OF FUSED HETEAROMATIC AMINES AS NOVEL MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS

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Page/Page column 12; 17; 18, (2010/11/08)

Novel derivatives of cyclic amines, pharmaceutical compositions, processes for their preparation, and use thereof in treating muscarinic acetylcholine receptor mediated diseases are provided.

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