892296-09-2

Basic information

• Product Name: 8-methoxy-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]coumarin
• CAS NO: 892296-09-2
• Molecular Weight: 350.331
• Mol File: 892296-09-2.mol

Chemical Properties

• CAS DataBase Reference: 8-methoxy-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]coumarin(CAS DataBase Reference)
• NIST Chemistry Reference: 8-methoxy-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]coumarin(892296-09-2)
• EPA Substance Registry System: 8-methoxy-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]coumarin(892296-09-2)

Safety Data

• Hazardous Substances Data: 892296-09-2(Hazardous Substances Data)

Upstream product

• 2555-20-6 8-methoxy-2-oxo-2H-chromene-3-carboxylic acid 
• 5373-87-5 4-methoxybenzamidoxime 

Relevant articles and documents

Isomeric 3-isoxadiazolylcoumarins and their derivatives

Here, we represent preparative methods of synthesis of isomeric 3-isoxadiazolylcoumarins and their derivatives. Two new synthetic methods have been developed for 3-[1,2,4-oxadiazol-5-yl]coumarins I. The first method is based on a three-component condensation of coumarin-;3-carboxylic acids, 1,1'-carbonyldiimidazole, and amidoximes. The second method essentially uses the interaction of 5-cyanomethyl-1,2,4-oxadiazoles with salicylic aldehydes. General approach for preparation of 3-[1,2,4-oxadiazol-3-yl]coumarins II has been worked out. Moreover, aforementioned synthetic ways open the way for the synthesis of 2-iminoderivatives III and IV not described before, those were diversified by reaction of nucleophilic substitution of 2-imino group with a numerous amino compounds.