89237-28-5Relevant academic research and scientific papers
ADDITION CONJUGUEE-ALKYLATION: STEREOCHIMIE DE LA REACTION DES LITHIENS D'ARYLACETONITRILES SUR LES CYCLENONES SUIVIE DU PIEGEAGE PAR L'IODURE DE METHYLE EN UNE SEULE OPERATION
Hatzigrigoriou, Evagelia,Roux-Schmitt, Marie-Claude,Wartski, Lya,Seyden-Penne, Jacqueline,Merienne, Claude
, p. 3415 - 3418 (1983)
The stereochemistry of trapping of enolates, resulting from reaction of lithiated arylacetonitriles to cyclenones, by methyl iodide, is examined.In a medium such as THF-HMPT, the trans 2,3-disubstituted cyclanones are obtained with good yields, and moreover in nearly all cases alkylation takes place under kinetic control.
