ADDITION CONJUGUEE-ALKYLATION: STEREOCHIMIE DE LA REACTION DES LITHIENS D'ARYLACETONITRILES SUR LES CYCLENONES SUIVIE DU PIEGEAGE PAR L'IODURE DE METHYLE EN UNE SEULE OPERATION

DOI: 10.1016/S0040-4020(01)91594-7

Source and publish data:

Tetrahedron p. 3415 - 3418 (1983)

Update date:2022-08-05

Topics:

Authors:

Hatzigrigoriou, Evagelia

Roux-Schmitt, Marie-Claude

Wartski, Lya

Seyden-Penne, Jacqueline

Merienne, Claude

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)91594-7

The stereochemistry of trapping of enolates, resulting from reaction of lithiated arylacetonitriles to cyclenones, by methyl iodide, is examined.In a medium such as THF-HMPT, the trans 2,3-disubstituted cyclanones are obtained with good yields, and moreover in nearly all cases alkylation takes place under kinetic control.

Full text of DOI:10.1016/S0040-4020(01)91594-7

Products guided by the article

Product name:phenyl-1'cyano-1'trimethyl-1',2,3 cyclohexanone

Cas No:89237-28-5

R&D Labs maybe for 89237-28-5

Luna Chemicals Co.,Ltd.

Contact:+86-570-4336358

Address:No.87 Building,Tianqian,Sidu Town
Xi'an Unique Electronic and Chemical Co., Ltd.

Contact:+86-029-88238008

Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
Jiangsu Zenji Pharmaceuticals LTD

Contact:+86-025-83172562; +1-224-888-1133(USA)

Address:No.5 Xinmofan Road
Lishui Nanming Chemical Co., Ltd(expird)

Contact:+86-0578-2134101，2697830

Address:No.19 Tongji Road Shuige Industrial zone
UNION PHARMPRO CO.,LTD

Contact:18710867521(wechat)

Address:Rm10516,Galaxy Tech Building #2,No.25 Tangyan Rd,Hi-Tech Zone,Xi'an, China

Relevant to this article

Experimental and Theoretical Studies of Dinuclear Gold(I) and Gold(II) Phosphorus Ylide Complexes. Oxidative Addition, Halide Exchange, and Structural Properties Including the Crystal and Molecular Structures of 2 and 2(CH3)Br

Doi:10.1021/ja00310a028
(1985)
Guanidine-catalyzed asymmetric trimethylsilylcyanation of carbonyl compounds

Doi:10.1002/adsc.200505161
(2005)
Doi:10.1021/jo50006a003
(1951)
4-Quinazolinyloxy-diaryl ureas as novel BRAF^V600E inhibitors

Doi:10.1016/j.bmcl.2011.07.019
(2011)
Nitration of Methyl 2-Furoate with Acetyl Nitrate. On the Configurations of Six Isolated Intermediary Adducts

Doi:10.1021/jo00183a028
(1984)
Quinazolin-4(3H)-one based agents bearing thiadiazole-urea: Synthesis and evaluation of anti-proliferative and antiangiogenic activity

Doi:10.1016/j.bioorg.2020.104553
(2021)

Article Doi