892498-86-1

Basic information

• Product Name: 5-amino-3H-thiazolo[4,5-d]pyrimidine-2-thione
• CAS NO: 892498-86-1
• Molecular Weight: 184.246
• Mol File: 892498-86-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-amino-3H-thiazolo[4,5-d]pyrimidine-2-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-3H-thiazolo[4,5-d]pyrimidine-2-thione(892498-86-1)
• EPA Substance Registry System: 5-amino-3H-thiazolo[4,5-d]pyrimidine-2-thione(892498-86-1)

Safety Data

• Hazardous Substances Data: 892498-86-1(Hazardous Substances Data)

Upstream product

• 140-89-6 potassium ethyl xanthogenate 
• 1004-01-9 5-bromopyrimidine-2,4-diamine 

Downstream Products

• 848691-22-5 5-aminothiazolo[4.5-d]pyrimidine-2,7-(3H,6H)-dione 

Relevant articles and documents

Development of a robust and sustainable process for nucleoside formation

A practical and robust process for the synthesis of an Isatoribine pro-drug was demonstrated. The process relies on a streamlined glycosylation carried out in xylene and an effective regioselective enzymatic hydrolysis that can be run in a semicontinuous way. Analysis of the process mass intensity established the high impact from an environmental standpoint of our process improvement.

3, 5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED-3H-OXAZOLO AND 3H-THIAZOLO [4,5-d]PYRIMIDIN-2-ONE COMPOUNDS AND PRODRUGS THEREOF

The invention is directed to 3,5-disubstituted and 3,5,7-trisubstituted-3-H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic