89260-45-7

Usage

Uses

Used in Pharmaceutical Industry:
4-(1H-Pyrazol-3-yl)aniline hydrochloride is used as a reactant in the synthesis of pharmaceuticals for its ability to participate in various chemical reactions, contributing to the development of new medicinal compounds.
Used in Chemical Industry:
In the chemical industry, 4-(1H-Pyrazol-3-yl)aniline hydrochloride is utilized as a building block for the production of a wide range of chemical products, thanks to its reactivity and capacity to engage in multiple chemical processes.
Used in Research and Development:
4-(1H-Pyrazol-3-yl)aniline hydrochloride is employed as a research compound in both the pharmaceutical and chemical sectors, aiding in the advancement of new technologies and the discovery of novel applications.
Used in Dyes and Pigments Production:
4-(1H-PYRAZOL-3-YL)ANILINE HYDROCHLORIDE is used as a precursor in the production of dyes and pigments, capitalizing on its chemical properties to create a variety of colorants for different applications.
Used in Agrochemicals Production:
4-(1H-Pyrazol-3-yl)aniline hydrochloride is also utilized in the creation of agrochemicals, where its chemical properties are harnessed to develop products for agricultural use.
Safety Note:
It is crucial to handle 4-(1H-Pyrazol-3-yl)aniline hydrochloride with care due to its potential hazards if not properly managed and stored, emphasizing the need for proper safety measures during its use.

Upstream product

• 20583-31-7 3-(4-nitrophenyl)-1H-pyrazole 
• 20583-31-7 5⁽³⁾-(4-nitrophenyl)-1H-pyrazole 
• 68760-11-2 1-(4-nitrophenyl)-3-N,N-dimethylamino-2-propen-1-one 
• 100-19-6 (4-nitrophenyl)ethanone 

Downstream Products

• 841295-52-1 5-(4-(+/-)-(5-nitro-2,4,6,7-tetramethyldihydrobenzofuran-2-ylmethyl)aminophenyl)pyrazole 
• 936214-94-7 5-(4-(5-nitro-2,2,6,7-tetramethyldihydrobenzofuran-4-ylmethyl)-N-acetylaminophenyl)-1-(tetrahydropyran-2-yl)pyrazole 
• 936214-93-6 5-(4-(5-nitro-2,2,6,7-tetramethyldihydrobenzofuran-4-ylmethyl)aminophenyl)-1-(tetrahydropyran-2-yl)pyrazole 
• 936214-54-9 5-(4-(5-amino-2,2,6,7-tetramethyldihydrobenzofuran-4-ylmethyl)-N-acetylaminophenyl)pyrazole 
• 936214-92-5 5-(4-(5-nitro-2,2,6,7-tetramethyldihydrobenzofuran-4-ylmethyl)aminophenyl)pyrazole 
• 936214-42-5 5-(4-(5-amino-2,2,6,7-tetramethyldihydrobenzofuran-4-ylmethyl)aminophenyl)pyrazole 
• 1181327-61-6 N-(4-(1H-pyrazol-5-yl)phenyl)-3-(8-((3,4-dimethoxyphenyl)amino)imidazo[1,2-a]pyrazin-6-yl)benzamide 
• 89260-46-8 3-(3-Aminophenyl)-pyrazole 

Relevant academic research and scientific papers

EXO-AZA SPIRO INHIBITORS OF MENIN-MLL INTERACTION

Provided are compounds of Formula (I), pharmaceutical compositions comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.

Phenylalaninamide pesticides and a preparing method thereof

The invention relates to the technical fields of organic synthesis and application techniques, and particularly relates to phenylalaninamide pesticides and a preparing method thereof. Phenylalanine, substituted phenylacetic acid, and the like are adopted

Phenylazole compounds, process for producing the same and drugs for hyperlipemia

Phenylazole compounds represented by general formula (1) or pharmaceutically acceptable salts thereof and drugs for hyperlipemia which contain these compounds as the active ingredient, wherein A represents imidazolyl, pyrazolyl, etc.; B represents (1a) or (1b) (wherein R2and R3represent each hydrogen, C1-6alkyl, etc; and k is 0 or an integer of 1 to 15); Y represents O, S, a bond, etc.; and Z represents an optionally substituted and saturated or unsaturated heterocycle containing 1 to 4 N, O or S atoms. Among all, compounds wherein Z is substituted chroman-2-yl, 2,3-dihydrobenzofuran-2-yl, etc. have an effect of inhibiting the formation of lipid peroxides too.

p-CYMENE RUTHENIUM(II) COMPLEXES WITH 3-SUBSTITUTED PYRAZOLE LIGANDS

The synthesis and characterisation of new mono- and dinuclear p-cymene-ruthenium(II) complexes (p-cymene = MeC6H4Pri-p) containing 3-substituted pyrazoles (LH) or pyrazolates (L) as ligands are reported .The new complexes belong to one of the following families (not all possible combinations): 6-p-cymene)RuCl2(LH)> (1-5),6-p-cymene)RuCl(LH)2>BF4 (6-11), 6-p-cymene)RuL(acac)> (acac = acetylacetonate) (12-15), 6-p-cymene)Ru(acac)(LH)>BF4 (16-19), 6-p-cymene)Ru(LH)3>2 (20-22), 6-p-cymene)RuL(LH)2>BF4 (23-25), 6-p-cymene)RuL2(LH)> (26-28), and the dinuclear 6-p-cymene)RuCl(μ-L)2M(CO)2> (M = Rh, Ir) (29-34).For the ruthenium-iridium complexes 6-p-cymene)RuCl(μ-ClPhpz)2Ir(CO)2> (33) and 6-p-cymene)RuCl(μ-MePhpz)2Ir(CO)2> (34) an equilibrium in solution is reached between two isomers that implies a reversible metal-metal bond formation accompanied by halide migration.