89265-35-0

Basic information

• Product Name: 2-(METHYLSULFONYL)BENZENESULFONYL CHLORIDE
• Synonyms: o-Chlorosulfonylphenyl methyl sulfone.;2-Methysulfonylbenzenesulfonyl chloride;2-(Methylsulfonyl)benzenesulfonyl chloride,95%;2-(Methylsulphonyl)benzenesulphonyl chloride 95%;2-(Chlorosulphonyl)phenyl methyl sulphone;2-(Methylsulfonyl)benzenesulfonyl chloride, 95% 2.5GR;2-(Methylsulphonyl)benzenesulphonylchloride95%;2-(Methylsulfonyl)benzene-1-sulfonyl chloride
• CAS NO: 89265-35-0
• Molecular Formula: C₇H₇ClO₄S₂
• Molecular Weight: 254.71
• Product Categories: Benzenesulfonyl chloride
• Mol File: 89265-35-0.mol

Chemical Properties

• Melting Point: 133-138 °C
• Boiling Point: 442 °C at 760 mmHg
• Flash Point: 221.1 °C
• Appearance: Off-white to yellow-brown/Crystalline Powder
• Density: 1.4936 (estimate)
• Vapor Pressure: 1.35E-07mmHg at 25°C
• Refractive Index: 1.554
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 2-(METHYLSULFONYL)BENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(METHYLSULFONYL)BENZENESULFONYL CHLORIDE(89265-35-0)
• EPA Substance Registry System: 2-(METHYLSULFONYL)BENZENESULFONYL CHLORIDE(89265-35-0)

Safety Data

• Hazard Codes: Xi,C
• Statements: 36/37/38-34
• Safety Statements: 37/39-26-45-36/37/39
• RIDADR: UN3261
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 89265-35-0(Hazardous Substances Data)

Usage

Chemical Properties

off-white to yellowish-brown crystalline powder

InChI:InChI=1/C7H7ClO4S2/c1-13(9,10)6-4-2-3-5-7(6)14(8,11)12/h2-5H,1H3

Upstream product

• 95-50-1 1,2-dichloro-benzene 
• 60036-47-7 o-methylsulphonylphenyl methyl sulphide 
• 17733-22-1 2-chlorothioanisole 
• 17482-05-2 o-chlorophenyl methyl sulfone 
• 2987-49-7 2-(methylsulfonyl)aniline 
• 282719-68-0 benzyl o-methylsulfonylphenyl sulfide 
• 99862-30-3 1-butylsulfanyl-2-methylsulfanyl-benzene 

Downstream Products

• 103008-83-9 2-(methylsulfonyl)benzenesulfonamide 
• 289638-43-3 FG 1465 
• 321707-17-9 C₁₆H₁₉NO₅S₂ 
• 1380539-39-8 C₁₉H₂₂F₃NO₅S₂ 
• 1310366-74-5 N-[(tert-butoxy)carbonyl](2-methanesulfonylbenzene)sulfonamido (2S)-2-{[(tert-butoxy)carbonyl](methyl)amino}-4-methylpentanoate 
• 1310366-87-0 N-[(tert-butoxy)carbonyl](2-methanesulfonylbenzene)sulfonamido N,N-dimethylcarbamate 
• 1023794-89-9 C₁₆H₁₈N₂O₇S₂ 
• 1046353-92-7 5'-deoxy-5'-[2-(methylsulfonyl)benzenesulfonamido]thymidine 
• 599183-17-2 2-methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide 

Relevant articles and documents

Development of the large-scale preparation of 2-(Methanesulfonyl) benzenesulfonyl chloride

A practical and scalable process is described for the preparation of 2-(methansulfonyl)benzenesulfonyl chloride, a key building block used in the synthesis of several drug candidates. The material is prepared by an efficient four-step sequence from inexpe

Sulfur containing compounds

This invention is directed to novel and known stufur containing compounds and pharmaceutically acceptable salts thereof that have utility as antifungals and as antiproliferative agents against mammalian cells, in particular cancer cells and most particularly leukemia-derived cells. The invention provides a method for synthesizing certain of the sulfur containing compounds that is more efficient than previously known methods.

Process for the preparation of 2-[alkyl(aryl)]sulfonylbenzene-sulfonyl chlorides and their intermediates

A process for the preparation of 2-[alkyl(aryl)]sulfonylbenzene sulfonyl chlorides of the following formula is provided: in which R is alkyl or aryl substituted at the ortho or meta positions with alkyl, aryl, NHAc or alkoxy, comprising the steps of: a) r

New and more potent antifungal bisulfides

From a design principle described in an earlier paper, a new series of substituted aryl methyl disulfides have been prepared and tested against Aspergillus niger and Aspergillus flavus. Methyl p-nitrophenyl disulfide is more potent (by an order of magnitude) than the fungitoxic natural product (CH3SCH2S)2. With the present rationale in hand, one can anticipate which Polycarpamine is an effective antifungal agent. CSIRO 2000.