89277-95-2Relevant academic research and scientific papers
Cu2O/TiO2 nanoparticles as visible light photocatalysts concerning C(sp2)-P bond formation
Hosseini-Sarvari, Mona,Jafari, Fattaneh,Mohajeri, Afshan,Hassani, Nasim
, p. 4044 - 4051 (2018/08/24)
A novel and efficient method has been developed for the construction of an aromatic-phosphorus (Ar-P) bond under visible light irradiation using Cu2O/TiO2 nanoparticles as inexpensive and available photocatalysts. This protocol is a simple system without the use of any base, ligand, oxidant, or special conditions. This is the first report for the synthesis of arylphosphonates from arylhydrazines in visible light irradiation.
Novel approach to metal-induced oxidative phosphorylation of aromatic compounds
Khrizanforov,Strekalova,Kholin,Khrizanforova,Kadirov,Gryaznova,Budnikova
, p. 133 - 141 (2016/11/03)
We propose a new approach to the phosphorylation of benzenes bearing both electron withdrawing and electron donating substituents on the ring and some coumarins (coumarin, 6-methylcoumarin, 7-methylcoumarin) under the action of dialkyl H-phosphonate (RO)
Synthesis and evaluation of phosphorus containing, specific CDK9/CycT1 inhibitors
Németh, Gábor,Greff, Zoltán,Sipos, Anna,Varga, Zoltán,Székely, Rita,Sebestyén, Mónika,Jászay, Zsuzsa,Béni, Szabolcs,Nemes, Zoltán,Pirat, Jean-Luc,Volle, Jean-No?l,Virieux, David,Gyuris, ágnes,Kelemenics, Katalin,áy, éva,Minarovits, Janos,Szathmary, Susan,Kéri, Gy?rgy,Orfi, László
, p. 3939 - 3965 (2014/06/09)
Although there is a significant effort in the design of a selective CDK9/CycT1 inhibitor, no compound has been proven to be a specific inhibitor of this kinase so far. The aim of this research was to develop novel and selective phosphorus containing CDK9/CycT1 inhibitors. Molecules bearing phosphonamidate, phosphonate, and phosphinate moieties were synthesized. Prepared compounds were evaluated in an enzymatic CDK9/CycT1 assay. The most potent molecules were tested in cell-based toxicity and HIV proliferation assays. Selectivity of shortlisted compounds against CDKs and other kinases was tested. The best compound was shown to be a highly specific, ATP-competitive inhibitor of CDK9/CycT1 with antiviral activity.
An improved procedure for the synthesis of aryl phosphonates by palladium-catalysed cross-coupling of aryl halides and diethyl phosphite in polyethylene glycol
Wang, Ping,Lu, Jie,Zhang, Zhan-Hui
, p. 359 - 361 (2013/07/26)
A general and greener protocol for the synthesis of aryl phosphonates by the cross-coupling of aryl halides and diethyl phosphite using tetrakis(triphenylphosphine)palladiume/triethylamine/polyethylene glycol 600 [Pd(PPh3)4/ Et3N/PEG 600] as an efficient catalytic system has been developed. This procedure also avoids hazardous solvents and is therefore an eco-friendly alternative to the existing methods.
Hypervalent iodine in synthesis. 52. Palladium-catalyzed arylation of O,O-dialkyl phosphites with diaryliodonium salts: A convenient method for synthesis of arylphosphonates
Zhou,Chen
, p. 3289 - 3294 (2007/10/03)
Palladium-catalyzed coupling reaction of diaryliodonium salts with O,O-dialkyl phosphites gave arylphosphonates in good yields.
Phosphorus analogues of γ-aminobutyric acid, a new class of anticonvulsants
Cates,Li,Yakshe,et al.
, p. 654 - 659 (2007/10/02)
A series of phosphorus compounds, designed as analogues of γ-aminobutyric acid (GABA) in that they possess a P=O moeity separated by three atoms from an amino or acetamido group, was synthesized and tested by using in vitro GABA(A) and GABA(B) receptor bi
