89278-13-7

Upstream product

• 32121-27-0 α-phenoxy-α-phenylacetonitrile 
• 88-73-3 2-Chloronitrobenzene 
• 13031-13-5 2-methoxy-2-phenylacetonitrile 

Relevant academic research and scientific papers

Multiple reaction pathways between the carbanions of α-alkoxy- α-phenylacetonitrile and o-chloronitrobenzene

Carbanions of α-methoxy-and α-phenoxy-α- phenylacetonitriles undergo a variety of reactions with o-chloronitrobenzene by initial formation of σH adducts and slower formation of σCl adducts. Reversible formation of σH adduc

Vicarious Nucleophilic Substitution of Hydrogen in Nitroarenes with α-Substituted Nitriles and Esters. Direct α-Cyanoalkylation and α-Carbalkoxyalkylation of Nitroarenes

Carbanions generated from alkanenitriles bearing α-chloro, α-OR, or α-SR groups and from aliphatic esters bearing α-SR groups react with mononitroarenes to replace hydrogen atoms of the nitroaromatic ring ortho or para to the nitro group with α-cyanoalkyl or α-carbalkoxyalkyl substituents.The nucleophilic replacement of hydrogen with such carbanions proceeds faster than substitution of halogen ortho or para to the nitro group.